Towards Eliminating Bias in Cluster Analysis of TB Genotyped Data

Cari van Schalkwyk; Madeleine Cule; Alex Welte; Paul van Helden; Gian van der Spuy; Pieter Uys

doi:10.1371/journal.pone.0034109

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Peer-reviewed

Research Article

Towards Eliminating Bias in Cluster Analysis of TB Genotyped Data

Cari van Schalkwyk ,

Contributed equally to this work with: Cari van Schalkwyk, Madeleine Cule

* E-mail: carivs@sun.ac.za

Affiliation The South African Department of Science and Technology/National Research Foundation (DST/NRF) Centre of Excellence in Epidemiological Modelling and Analysis, Faculty of Science, University of Stellenbosch, Stellenbosch, South Africa
⨯
Madeleine Cule ,

Contributed equally to this work with: Cari van Schalkwyk, Madeleine Cule

Affiliations African Institute for Mathematical Sciences, Muizenberg, South Africa, Department of Statistics, University of Oxford, Oxford, United Kingdom
⨯
Alex Welte,

Affiliation The South African Department of Science and Technology/National Research Foundation (DST/NRF) Centre of Excellence in Epidemiological Modelling and Analysis, Faculty of Science, University of Stellenbosch, Stellenbosch, South Africa
⨯
Paul van Helden,

Affiliation DST/NRF Centre of Excellence in Biomedical Tuberculosis Research/MRC Centre of Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Stellenbosch, South Africa
⨯
Gian van der Spuy,

Affiliation DST/NRF Centre of Excellence in Biomedical Tuberculosis Research/MRC Centre of Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Stellenbosch, South Africa
⨯
Pieter Uys

Affiliation The South African Department of Science and Technology/National Research Foundation (DST/NRF) Centre of Excellence in Epidemiological Modelling and Analysis, Faculty of Science, University of Stellenbosch, Stellenbosch, South Africa
⨯

Towards Eliminating Bias in Cluster Analysis of TB Genotyped Data

Cari van Schalkwyk,
Madeleine Cule,
Alex Welte,
Paul van Helden,
Gian van der Spuy,
Pieter Uys

Published: March 29, 2012
https://doi.org/10.1371/journal.pone.0034109

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Tuberculosis
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Tuberculosis diagnosis and management
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Restriction fragment length polymorphism analysis
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Clustering algorithms
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Sputum
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Genotyping
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HIV diagnosis and management
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