HLA-DRB1-DQB1 Haplotypes Confer Susceptibility and Resistance to Multiple Sclerosis in Sardinia

Eleonora Cocco; Claudia Sardu; Enrico Pieroni; Maria Valentini; Raffaele Murru; Gianna Costa; Stefania Tranquilli; Jessica Frau; Giancarlo Coghe; Nicola Carboni; Matteo Floris; Paolo Contu; Maria Giovanna Marrosu

doi:10.1371/journal.pone.0033972

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Open Access

Peer-reviewed

Research Article

HLA-DRB1-DQB1 Haplotypes Confer Susceptibility and Resistance to Multiple Sclerosis in Sardinia

Eleonora Cocco,

Affiliation Department Public Health, Clinical and Molecular Medicine, University of Cagliari, Cagliari, Italy
⨯
Claudia Sardu,

Affiliation Department Public Health, Clinical and Molecular Medicine, University of Cagliari, Cagliari, Italy
⨯
Enrico Pieroni,

Affiliation CRS4 (Centro di Ricerca, Sviluppo e Studi Superiori in Sardegna), Science and Technology Park Polaris - Piscina Manna, Pula (Cagliari), Italy
⨯
Maria Valentini,

Affiliation CRS4 (Centro di Ricerca, Sviluppo e Studi Superiori in Sardegna), Science and Technology Park Polaris - Piscina Manna, Pula (Cagliari), Italy
⨯
Raffaele Murru,

Affiliation Department Public Health, Clinical and Molecular Medicine, University of Cagliari, Cagliari, Italy
⨯
Gianna Costa,

Affiliation Department Public Health, Clinical and Molecular Medicine, University of Cagliari, Cagliari, Italy
⨯
Stefania Tranquilli,

Affiliation Department Public Health, Clinical and Molecular Medicine, University of Cagliari, Cagliari, Italy
⨯
Jessica Frau,

Affiliation Department Public Health, Clinical and Molecular Medicine, University of Cagliari, Cagliari, Italy
⨯
Giancarlo Coghe,

Affiliation Department Public Health, Clinical and Molecular Medicine, University of Cagliari, Cagliari, Italy
⨯
Nicola Carboni,

Affiliation Department Public Health, Clinical and Molecular Medicine, University of Cagliari, Cagliari, Italy
⨯
Matteo Floris,

Affiliation CRS4 (Centro di Ricerca, Sviluppo e Studi Superiori in Sardegna), Science and Technology Park Polaris - Piscina Manna, Pula (Cagliari), Italy
⨯
Paolo Contu,

Affiliation Department Public Health, Clinical and Molecular Medicine, University of Cagliari, Cagliari, Italy
⨯
Maria Giovanna Marrosu

* E-mail: gmarrosu@unica.it

Affiliation Department Public Health, Clinical and Molecular Medicine, University of Cagliari, Cagliari, Italy
⨯

HLA-DRB1-DQB1 Haplotypes Confer Susceptibility and Resistance to Multiple Sclerosis in Sardinia

Eleonora Cocco,
Claudia Sardu,
Enrico Pieroni,
Maria Valentini,
Raffaele Murru,
Gianna Costa,
Stefania Tranquilli,
Jessica Frau,
Giancarlo Coghe,
Nicola Carboni

Published: April 11, 2012
https://doi.org/10.1371/journal.pone.0033972

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Haplotypes
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Medical risk factors
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Multiple sclerosis
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Heterozygosity
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Variant genotypes
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Genetic predisposition
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Homozygosity
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Sequence alignment
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