Exome Sequencing Identifies Compound Heterozygous Mutations in CYP4V2 in a Pedigree with Retinitis Pigmentosa

Yun Wang; Liheng Guo; Su-Ping Cai; Meizhi Dai; Qiaona Yang; Wenhan Yu; Naihong Yan; Xiaomin Zhou; Jin Fu; Xinwu Guo; Pengfei Han; Jun Wang; Xuyang Liu

doi:10.1371/journal.pone.0033673

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Open Access

Peer-reviewed

Research Article

Exome Sequencing Identifies Compound Heterozygous Mutations in CYP4V2 in a Pedigree with Retinitis Pigmentosa

Yun Wang ,

Contributed equally to this work with: Yun Wang, Liheng Guo, Su-Ping Cai, Meizhi Dai

Affiliation Ophthalmic Laboratories & Department of Ophthalmology, State Key Laboratory of Biotherapy, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People’s Republic of China
⨯
Liheng Guo ,

Contributed equally to this work with: Yun Wang, Liheng Guo, Su-Ping Cai, Meizhi Dai

Affiliation Ophthalmic Laboratories & Department of Ophthalmology, State Key Laboratory of Biotherapy, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People’s Republic of China
⨯
Su-Ping Cai ,

Contributed equally to this work with: Yun Wang, Liheng Guo, Su-Ping Cai, Meizhi Dai

Affiliation Shenzhen Eye Hospital, Jinan University, Shenzhen, People’s Republic of China
⨯
Meizhi Dai ,

Contributed equally to this work with: Yun Wang, Liheng Guo, Su-Ping Cai, Meizhi Dai

Affiliation BGI-Shenzhen, Shenzhen, Guangdong Province, People’s Republic of China
⨯
Qiaona Yang,

Affiliation Ophthalmic Laboratories & Department of Ophthalmology, State Key Laboratory of Biotherapy, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People’s Republic of China
⨯
Wenhan Yu,

Affiliation Ophthalmic Laboratories & Department of Ophthalmology, State Key Laboratory of Biotherapy, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People’s Republic of China
⨯
Naihong Yan,

Affiliation Ophthalmic Laboratories & Department of Ophthalmology, State Key Laboratory of Biotherapy, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People’s Republic of China
⨯
Xiaomin Zhou,

Affiliation Ophthalmic Laboratories & Department of Ophthalmology, State Key Laboratory of Biotherapy, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People’s Republic of China
⨯
Jin Fu,

Affiliation BGI-Shenzhen, Shenzhen, Guangdong Province, People’s Republic of China
⨯
Xinwu Guo,

Affiliation BGI-Shenzhen, Shenzhen, Guangdong Province, People’s Republic of China
⨯
Pengfei Han,

Affiliation BGI-Shenzhen, Shenzhen, Guangdong Province, People’s Republic of China
⨯
Jun Wang ,

* E-mail: xliu1213@yahoo.com.cn (XL); wangj@genomics.org.cn (JW)

Affiliation BGI-Shenzhen, Shenzhen, Guangdong Province, People’s Republic of China
⨯
Xuyang Liu

* E-mail: xliu1213@yahoo.com.cn (XL); wangj@genomics.org.cn (JW)

Affiliation Shenzhen Eye Hospital, Jinan University, Shenzhen, People’s Republic of China
⨯

Exome Sequencing Identifies Compound Heterozygous Mutations in CYP4V2 in a Pedigree with Retinitis Pigmentosa

Yun Wang,
Liheng Guo,
Su-Ping Cai,
Meizhi Dai,
Qiaona Yang,
Wenhan Yu,
Naihong Yan,
Xiaomin Zhou,
Jin Fu,
Xinwu Guo

Published: May 31, 2012
https://doi.org/10.1371/journal.pone.0033673

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