Optogenetic Mimicry of the Transient Activation of Dopamine Neurons by Natural Reward Is Sufficient for Operant Reinforcement

• Kyung Man Kim,

  Affiliation Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, South Korea

  ⨯
• Michael V. Baratta,

  Affiliation Media Lab, McGovern Institute, and Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  ⨯
• Aimei Yang,

  Affiliation Media Lab, McGovern Institute, and Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  ⨯
• Doheon Lee,

  Affiliation Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, South Korea

  ⨯
• Edward S. Boyden ,

  * E-mail: esb@media.mit.edu (ESB); fiorillo@kaist.ac.kr (CDF)

  Affiliation Media Lab, McGovern Institute, and Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  ⨯
• Christopher D. Fiorillo

  * E-mail: esb@media.mit.edu (ESB); fiorillo@kaist.ac.kr (CDF)

  Affiliation Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, South Korea

  ⨯