Targeting Bone Alleviates Osteoarthritis in Osteopenic Mice and Modulates Cartilage Catabolism

Thomas Funck-Brentano; Hilène Lin; Eric Hay; Marie-Dominique Ah Kioon; Corinne Schiltz; Didier Hannouche; Rémy Nizard; Frédéric Lioté; Philippe Orcel; Marie-Christine de Vernejoul; Martine Esther Cohen-Solal

doi:10.1371/journal.pone.0033543

Loading metrics

Open Access

Peer-reviewed

Research Article

Targeting Bone Alleviates Osteoarthritis in Osteopenic Mice and Modulates Cartilage Catabolism

Thomas Funck-Brentano,

Affiliation INSERM U606, Centre Viggo Petersen and Université Paris-Diderot Paris 7, Hôpital Lariboisière, Paris, France
⨯
Hilène Lin,

Affiliation INSERM U606, Centre Viggo Petersen and Université Paris-Diderot Paris 7, Hôpital Lariboisière, Paris, France
⨯
Eric Hay,

Affiliation INSERM U606, Centre Viggo Petersen and Université Paris-Diderot Paris 7, Hôpital Lariboisière, Paris, France
⨯
Marie-Dominique Ah Kioon,

Affiliation INSERM U606, Centre Viggo Petersen and Université Paris-Diderot Paris 7, Hôpital Lariboisière, Paris, France
⨯
Corinne Schiltz,

Affiliation INSERM U606, Centre Viggo Petersen and Université Paris-Diderot Paris 7, Hôpital Lariboisière, Paris, France
⨯
Didier Hannouche,

Affiliation Department of Orthopedics, Centre Viggo Petersen and Université Paris-Diderot Paris 7, Hôpital Lariboisière, Paris, France
⨯
Rémy Nizard,

Affiliation Department of Orthopedics, Centre Viggo Petersen and Université Paris-Diderot Paris 7, Hôpital Lariboisière, Paris, France
⨯
Frédéric Lioté,

Affiliation INSERM U606, Centre Viggo Petersen and Université Paris-Diderot Paris 7, Hôpital Lariboisière, Paris, France
⨯
Philippe Orcel,

Affiliation Department of Rheumatology, Centre Viggo Petersen and Université Paris-Diderot Paris 7, Hôpital Lariboisière, Paris, France
⨯
Marie-Christine de Vernejoul,

Affiliation INSERM U606, Centre Viggo Petersen and Université Paris-Diderot Paris 7, Hôpital Lariboisière, Paris, France
⨯
Martine Esther Cohen-Solal

* E-mail: martine.cohen-solal@inserm.fr

Affiliation INSERM U606, Centre Viggo Petersen and Université Paris-Diderot Paris 7, Hôpital Lariboisière, Paris, France
⨯

Targeting Bone Alleviates Osteoarthritis in Osteopenic Mice and Modulates Cartilage Catabolism

Thomas Funck-Brentano,
Hilène Lin,
Eric Hay,
Marie-Dominique Ah Kioon,
Corinne Schiltz,
Didier Hannouche,
Rémy Nizard,
Frédéric Lioté,
Philippe Orcel,
Marie-Christine de Vernejoul

Published: March 14, 2012
https://doi.org/10.1371/journal.pone.0033543

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cartilage
Is the Subject Area "Cartilage" applicable to this article?

Thanks for your feedback.
Bone resorption
Is the Subject Area "Bone resorption" applicable to this article?

Thanks for your feedback.
Estradiol
Is the Subject Area "Estradiol" applicable to this article?

Thanks for your feedback.
Osteoarthritis
Is the Subject Area "Osteoarthritis" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Skeletal joints
Is the Subject Area "Skeletal joints" applicable to this article?

Thanks for your feedback.
Osteoclasts
Is the Subject Area "Osteoclasts" applicable to this article?

Thanks for your feedback.
Ovariectomy
Is the Subject Area "Ovariectomy" applicable to this article?

Thanks for your feedback.