Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice

Rachel B. Reinert; Jeannelle Kantz; Amanda Ackermann Misfeldt; Greg Poffenberger; Maureen Gannon; Marcela Brissova; Alvin C. Powers

doi:10.1371/journal.pone.0033529

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Open Access

Peer-reviewed

Research Article

Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice

Rachel B. Reinert,

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Jeannelle Kantz,

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Amanda Ackermann Misfeldt,

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Greg Poffenberger,

Affiliation Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Maureen Gannon,

Affiliations Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America
⨯
Marcela Brissova,

Affiliation Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Alvin C. Powers

* E-mail: al.powers@vanderbilt.edu

Affiliations Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America
⨯

Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice

Rachel B. Reinert,
Jeannelle Kantz,
Amanda Ackermann Misfeldt,
Greg Poffenberger,
Maureen Gannon,
Marcela Brissova,
Alvin C. Powers

Published: March 28, 2012
https://doi.org/10.1371/journal.pone.0033529

Reader Comments (2)

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24 Nov 2013
22:00 GMT
Most Recent

Generalizable to other organs Posted by stemcella on 24 Nov 2013 at 22:00 GMT
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31 Aug 2012
15:25 GMT
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tamoxifen delivery route and duration Posted by cmurtaugh on 31 Aug 2012 at 15:25 GMT

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