Mechanism of RPE Cell Death in α-Crystallin Deficient Mice: A Novel and Critical Role for MRP1-Mediated GSH Efflux

• Parameswaran G. Sreekumar,

  Affiliation Arnold and Mabel Beckman Macular Research Center, Doheny Eye Institute, Los Angeles, California, United States of America

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• Christine Spee,

  Affiliation Arnold and Mabel Beckman Macular Research Center, Doheny Eye Institute, Los Angeles, California, United States of America

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• Stephen J. Ryan,

  Affiliations Arnold and Mabel Beckman Macular Research Center, Doheny Eye Institute, Los Angeles, California, United States of America, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America

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• Susan P. C. Cole,

  Affiliation Division of Cancer Biology and Genetics, Queen's University Cancer Research Institute, Kingston, Canada

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• Ram Kannan,

  Affiliations Arnold and Mabel Beckman Macular Research Center, Doheny Eye Institute, Los Angeles, California, United States of America, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America

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• David R. Hinton

  * E-mail: dhinton@usc.edu

  Affiliations Arnold and Mabel Beckman Macular Research Center, Doheny Eye Institute, Los Angeles, California, United States of America, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America

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