Stearoyl-CoA Desaturase-1 (SCD1) Augments Saturated Fatty Acid-Induced Lipid Accumulation and Inhibits Apoptosis in Cardiac Myocytes

Hiroki Matsui; Tomoyuki Yokoyama; Kenichi Sekiguchi; Daisuke Iijima; Hiroaki Sunaga; Moeno Maniwa; Manabu Ueno; Tatsuya Iso; Masashi Arai; Masahiko Kurabayashi

doi:10.1371/journal.pone.0033283

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Peer-reviewed

Research Article

Stearoyl-CoA Desaturase-1 (SCD1) Augments Saturated Fatty Acid-Induced Lipid Accumulation and Inhibits Apoptosis in Cardiac Myocytes

Hiroki Matsui,

Affiliations Department of Medicine and Biological Sciences, Gunma University Graduate School of Medicine, Showa-machi, Maebashi, Japan, Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Showa-machi, Maebashi, Japan
⨯
Tomoyuki Yokoyama ,

* E-mail: tyokoyama@gunma-u.ac.jp

Affiliation Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Showa-machi, Maebashi, Japan
⨯
Kenichi Sekiguchi,

Affiliation Department of Medicine and Biological Sciences, Gunma University Graduate School of Medicine, Showa-machi, Maebashi, Japan
⨯
Daisuke Iijima,

Affiliation Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Showa-machi, Maebashi, Japan
⨯
Hiroaki Sunaga,

Affiliation Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Showa-machi, Maebashi, Japan
⨯
Moeno Maniwa,

Affiliation Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Showa-machi, Maebashi, Japan
⨯
Manabu Ueno,

Affiliation Department of Medicine and Biological Sciences, Gunma University Graduate School of Medicine, Showa-machi, Maebashi, Japan
⨯
Tatsuya Iso,

Affiliation Department of Medicine and Biological Sciences, Gunma University Graduate School of Medicine, Showa-machi, Maebashi, Japan
⨯
Masashi Arai,

Affiliation Department of Medicine and Biological Sciences, Gunma University Graduate School of Medicine, Showa-machi, Maebashi, Japan
⨯
Masahiko Kurabayashi

Affiliation Department of Medicine and Biological Sciences, Gunma University Graduate School of Medicine, Showa-machi, Maebashi, Japan
⨯

Stearoyl-CoA Desaturase-1 (SCD1) Augments Saturated Fatty Acid-Induced Lipid Accumulation and Inhibits Apoptosis in Cardiac Myocytes

Hiroki Matsui,
Tomoyuki Yokoyama,
Kenichi Sekiguchi,
Daisuke Iijima,
Hiroaki Sunaga,
Moeno Maniwa,
Manabu Ueno,
Tatsuya Iso,
Masashi Arai,
Masahiko Kurabayashi

Published: March 8, 2012
https://doi.org/10.1371/journal.pone.0033283

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