CXCL12 Mediates Trophic Interactions between Endothelial and Tumor Cells in Glioblastoma

Shyam Rao; Rajarshi Sengupta; Eun Joo Choe; B. Mark Woerner; Erin Jackson; Tao Sun; Jeffrey Leonard; David Piwnica-Worms; Joshua B. Rubin

doi:10.1371/journal.pone.0033005

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Open Access

Peer-reviewed

Research Article

CXCL12 Mediates Trophic Interactions between Endothelial and Tumor Cells in Glioblastoma

Shyam Rao ,

Contributed equally to this work with: Shyam Rao, Rajarshi Sengupta

Affiliation Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Rajarshi Sengupta ,

Contributed equally to this work with: Shyam Rao, Rajarshi Sengupta

Affiliation Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Eun Joo Choe,

Affiliation Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America
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B. Mark Woerner,

Affiliation Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Erin Jackson,

Affiliations Bridging Research with Imaging, Genomics and High-Throughput Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America, Molecular Imaging Center, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Tao Sun,

Affiliation Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Jeffrey Leonard,

Affiliation Department of Neurosurgery, Washington University School of Medicine, St. Louis, Missouri, United States of America
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David Piwnica-Worms,

Affiliations Bridging Research with Imaging, Genomics and High-Throughput Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America, Molecular Imaging Center, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Cell Biology & Physiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Joshua B. Rubin

* E-mail: rubin_j@kids.wustl.edu

Affiliations Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯

CXCL12 Mediates Trophic Interactions between Endothelial and Tumor Cells in Glioblastoma

Shyam Rao,
Rajarshi Sengupta,
Eun Joo Choe,
B. Mark Woerner,
Erin Jackson,
Tao Sun,
Jeffrey Leonard,
David Piwnica-Worms,
Joshua B. Rubin

Published: March 12, 2012
https://doi.org/10.1371/journal.pone.0033005

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Endothelial cells
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Glioblastoma multiforme
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Malignant tumors
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Immunohistochemistry techniques
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Trophic interactions
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