Renal Failure Affects the Enzymatic Activities of the Three First Steps in Hepatic Heme Biosynthesis in the Acute Intermittent Porphyria Mouse

• Carmen Unzu,

  Affiliation Gene Therapy and Hepatology Area, Centre for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain

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• Ana Sampedro,

  Affiliation Gene Therapy and Hepatology Area, Centre for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain

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• Eliane Sardh,

  Affiliations Department of Internal Medicine, Karolinska Institutet, Stockholm Söder Hospital, Stockholm, Sweden, Porphyria Centre Sweden, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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• Itsaso Mauleón,

  Affiliation Gene Therapy and Hepatology Area, Centre for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain

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• Rafael Enríquez de Salamanca,

  Affiliation Research Center, Hospital Universitario 12 de Octubre, Universidad Complutense, Madrid, Spain

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• Jesús Prieto,

  Affiliation Gene Therapy and Hepatology Area, Centre for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain

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• Eduardo Salido ,

  Contributed equally to this work with: Eduardo Salido, Pauline Harper, Antonio Fontanellas

  Affiliation Centre for Biomedical Research on Rare Diseases (CIBERER), University Hospital of Canarias, University of La Laguna, La Laguna, Spain

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• Pauline Harper ,

  Contributed equally to this work with: Eduardo Salido, Pauline Harper, Antonio Fontanellas

  Affiliation Porphyria Centre Sweden, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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• Antonio Fontanellas

  Contributed equally to this work with: Eduardo Salido, Pauline Harper, Antonio Fontanellas

  * E-mail: afontanellas@unav.es

  Affiliation Gene Therapy and Hepatology Area, Centre for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain

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