The Colocalization Potential of HIV-Specific CD8+ and CD4+ T-Cells is Mediated by Integrin β7 but Not CCR6 and Regulated by Retinoic Acid

Vanessa Sue Wacleche; Nicolas Chomont; Annie Gosselin; Patricia Monteiro; Mathieu Goupil; Hassen Kared; Cécile Tremblay; Nicole Bernard; Mohamed-Rachid Boulassel; Jean-Pierre Routy; Petronela Ancuta

doi:10.1371/journal.pone.0032964

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Open Access

Peer-reviewed

Research Article

The Colocalization Potential of HIV-Specific CD8⁺ and CD4⁺ T-Cells is Mediated by Integrin β7 but Not CCR6 and Regulated by Retinoic Acid

Vanessa Sue Wacleche,

Affiliations Department of Microbiology and Immunology, Université de Montréal, Montreal, Quebec, Canada, Centre Hospitalier de l'Université de Montréal (CHUM)-Research Center, Saint-Luc Hospital, Montreal, Quebec, Canada
⨯
Nicolas Chomont,

Affiliation VGTI-Florida, Port St Lucie, Florida, United States of America
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Annie Gosselin,

Affiliation Centre Hospitalier de l'Université de Montréal (CHUM)-Research Center, Saint-Luc Hospital, Montreal, Quebec, Canada
⨯
Patricia Monteiro,

Affiliations Department of Microbiology and Immunology, Université de Montréal, Montreal, Quebec, Canada, Centre Hospitalier de l'Université de Montréal (CHUM)-Research Center, Saint-Luc Hospital, Montreal, Quebec, Canada, INSERM Unit 743, Montréal, Quebec, Canada
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Mathieu Goupil,

Affiliation Department of Microbiology and Immunology, Université de Montréal, Montreal, Quebec, Canada
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Hassen Kared,

Affiliations Department of Microbiology and Immunology, Université de Montréal, Montreal, Quebec, Canada, Centre Hospitalier de l'Université de Montréal (CHUM)-Research Center, Saint-Luc Hospital, Montreal, Quebec, Canada
⨯
Cécile Tremblay,

Affiliations Department of Microbiology and Immunology, Université de Montréal, Montreal, Quebec, Canada, Centre Hospitalier de l'Université de Montréal (CHUM)-Research Center, Saint-Luc Hospital, Montreal, Quebec, Canada
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Nicole Bernard,

Affiliation Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
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Mohamed-Rachid Boulassel,

Affiliation Division of Hematology, McGill University Health Centre, Montreal, Quebec, Canada
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Jean-Pierre Routy,

Affiliations INSERM Unit 743, Montréal, Quebec, Canada, Division of Hematology, McGill University Health Centre, Montreal, Quebec, Canada, Immunodeficiency Service, Montreal Chest Institute, McGill University Health Centre, Montreal, Quebec, Canada
⨯
Petronela Ancuta

* E-mail: petronela.ancuta@umontreal.ca

Affiliations Department of Microbiology and Immunology, Université de Montréal, Montreal, Quebec, Canada, Centre Hospitalier de l'Université de Montréal (CHUM)-Research Center, Saint-Luc Hospital, Montreal, Quebec, Canada, INSERM Unit 743, Montréal, Quebec, Canada
⨯

The Colocalization Potential of HIV-Specific CD8⁺ and CD4⁺ T-Cells is Mediated by Integrin β7 but Not CCR6 and Regulated by Retinoic Acid

Vanessa Sue Wacleche,
Nicolas Chomont,
Annie Gosselin,
Patricia Monteiro,
Mathieu Goupil,
Hassen Kared,
Cécile Tremblay,
Nicole Bernard,
Mohamed-Rachid Boulassel,
Jean-Pierre Routy

Published: March 28, 2012
https://doi.org/10.1371/journal.pone.0032964

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HIV
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