Targeted Disruption of Ephrin B1 in Cells of Myeloid Lineage Increases Osteoclast Differentiation and Bone Resorption in Mice

Shaohong Cheng; Shien Lucy Zhao; Brittany Nelson; Chandrasekhar Kesavan; Xuezhong Qin; Jon Wergedal; Subburaman Mohan; Weirong Xing

doi:10.1371/journal.pone.0032887

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Peer-reviewed

Research Article

Targeted Disruption of Ephrin B1 in Cells of Myeloid Lineage Increases Osteoclast Differentiation and Bone Resorption in Mice

Shaohong Cheng,

Affiliation Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California, United States of America
⨯
Shien Lucy Zhao,

Affiliation Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California, United States of America
⨯
Brittany Nelson,

Affiliation Department of Physiology, Loma Linda University, Loma Linda, California, United States of America
⨯
Chandrasekhar Kesavan,

Affiliations Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California, United States of America, Department of Medicine, Loma Linda University, Loma Linda, California, United States of America
⨯
Xuezhong Qin,

Affiliations Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California, United States of America, Department of Medicine, Loma Linda University, Loma Linda, California, United States of America
⨯
Jon Wergedal,

Affiliations Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California, United States of America, Department of Medicine, Loma Linda University, Loma Linda, California, United States of America, Department of Biochemistry, Loma Linda University, Loma Linda, California, United States of America
⨯
Subburaman Mohan,

Affiliations Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California, United States of America, Department of Medicine, Loma Linda University, Loma Linda, California, United States of America, Department of Biochemistry, Loma Linda University, Loma Linda, California, United States of America, Department of Physiology, Loma Linda University, Loma Linda, California, United States of America
⨯
Weirong Xing

* E-mail: Weirong.Xing@va.gov

Affiliations Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California, United States of America, Department of Medicine, Loma Linda University, Loma Linda, California, United States of America
⨯

Targeted Disruption of Ephrin B1 in Cells of Myeloid Lineage Increases Osteoclast Differentiation and Bone Resorption in Mice

Shaohong Cheng,
Shien Lucy Zhao,
Brittany Nelson,
Chandrasekhar Kesavan,
Xuezhong Qin,
Jon Wergedal,
Subburaman Mohan,
Weirong Xing

Published: March 5, 2012
https://doi.org/10.1371/journal.pone.0032887

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Osteoclasts
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Cell differentiation
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Bone resorption
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Immunoprecipitation
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Cell disruption
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