The 5′ Flanking Region and Intron1 of the Bovine Prion Protein Gene (PRNP) Are Responsible for Negative Feedback Regulation of the Prion Protein

• Guangai Xue,

  Affiliations Department of Molecular Immunology, School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan, Viral Infectious Diseases Research Unit, RIKEN, 2-1 Hirosawa, Wako, Saitama, Japan

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• Yoko Aida,

  Affiliation Viral Infectious Diseases Research Unit, RIKEN, 2-1 Hirosawa, Wako, Saitama, Japan

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• Takashi Onodera,

  Affiliation Department of Molecular Immunology, School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan

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• Akikazu Sakudo

  * E-mail: sakudo@med.u-ryukyu.ac.jp

  Affiliation Laboratory of Biometabolic Chemistry, School of Health Sciences, Faculty of Medicine, University of the Ryukyus, Nishihara, Okinawa, Japan

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