Differential Contribution of the Repeats to Heparin Binding of HBHA, a Major Adhesin of Mycobacterium tuberculosis

Pierre Lebrun; Dominique Raze; Bernd Fritzinger; Jean-Michel Wieruszeski; Franck Biet; Alexander Dose; Mathieu Carpentier; Dirk Schwarzer; Fabrice Allain; Guy Lippens; Camille Locht

doi:10.1371/journal.pone.0032421

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Peer-reviewed

Research Article

Differential Contribution of the Repeats to Heparin Binding of HBHA, a Major Adhesin of Mycobacterium tuberculosis

Pierre Lebrun,

Affiliations INSERM U1019, Lille, France, CNRS UMR 8204, Lille, France, Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France, Univ Lille Nord de France, Lille, France
⨯
Dominique Raze,

Affiliations INSERM U1019, Lille, France, CNRS UMR 8204, Lille, France, Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France, Univ Lille Nord de France, Lille, France
⨯
Bernd Fritzinger,

Affiliations Univ Lille Nord de France, Lille, France, CNRS UMR8576 Structural and Functional Glycobiology, Villeneuve d'Ascq, France
⨯
Jean-Michel Wieruszeski,

Affiliations Univ Lille Nord de France, Lille, France, CNRS UMR8576 Structural and Functional Glycobiology, Villeneuve d'Ascq, France
⨯
Franck Biet,

Affiliation UR1282, Infectiologie Animale, Sante' Publique (IASP-311), INRA, Nouzilly, France
⨯
Alexander Dose,

Affiliation Interfaculty Institute for Biochemistry, University of Tübingen, Tübingen, Germany
⨯
Mathieu Carpentier,

Affiliations Univ Lille Nord de France, Lille, France, CNRS UMR8576 Structural and Functional Glycobiology, Villeneuve d'Ascq, France
⨯
Dirk Schwarzer,

Affiliation Interfaculty Institute for Biochemistry, University of Tübingen, Tübingen, Germany
⨯
Fabrice Allain,

Affiliations Univ Lille Nord de France, Lille, France, CNRS UMR8576 Structural and Functional Glycobiology, Villeneuve d'Ascq, France
⨯
Guy Lippens ,

Contributed equally to this work with: Guy Lippens, Camille Locht

* E-mail: guy.lippens@univ-lille1.fr

Affiliations Univ Lille Nord de France, Lille, France, CNRS UMR8576 Structural and Functional Glycobiology, Villeneuve d'Ascq, France
⨯
Camille Locht

Contributed equally to this work with: Guy Lippens, Camille Locht

Affiliations INSERM U1019, Lille, France, CNRS UMR 8204, Lille, France, Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France, Univ Lille Nord de France, Lille, France
⨯

Differential Contribution of the Repeats to Heparin Binding of HBHA, a Major Adhesin of Mycobacterium tuberculosis

Pierre Lebrun,
Dominique Raze,
Bernd Fritzinger,
Jean-Michel Wieruszeski,
Franck Biet,
Alexander Dose,
Mathieu Carpentier,
Dirk Schwarzer,
Fabrice Allain,
Guy Lippens

Published: March 5, 2012
https://doi.org/10.1371/journal.pone.0032421

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Heparin
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Mycobacterium tuberculosis
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Proline
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NMR spectroscopy
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Chemical dissociation
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