Development of a Humanized HLA-A2.1/DP4 Transgenic Mouse Model and the Use of This Model to Map HLA-DP4-Restricted Epitopes of HBV Envelope Protein

• Zhitao Ru,

  Affiliations State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China, INSERM U1014 (ex U542), Université Paris-Sud, Hôpital Paul Brousse, Villejuif, France

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• Wenjun Xiao,

  Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

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• Anthony Pajot,

  Affiliation INSERM U1014 (ex U542), Université Paris-Sud, Hôpital Paul Brousse, Villejuif, France

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• Zhihua Kou,

  Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

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• Shihui Sun,

  Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

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• Bernard Maillere,

  Affiliation Commissariat à l'Energie Atomique-Saclay, Institut de Biologie et Technologies, Service d'Ingénierie Moléculaire des Protéines, Gif-sur-Yvette, France

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• Guangyu Zhao,

  Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

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• David M. Ojcius,

  Affiliation Health Sciences Research Institute and School of Natural Sciences, University of California Merced, Merced, California, United States of America

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• Yu-chun Lone ,

  * E-mail: yu-chun.lone@inserm.fr (YL); yszhou@nic.bmi.ac.cn (YZ)

  Affiliation INSERM U1014 (ex U542), Université Paris-Sud, Hôpital Paul Brousse, Villejuif, France

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• Yusen Zhou

  * E-mail: yu-chun.lone@inserm.fr (YL); yszhou@nic.bmi.ac.cn (YZ)

  Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

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