Intranasal Administration of poly(I:C) and LPS in BALB/c Mice Induces Airway Hyperresponsiveness and Inflammation via Different Pathways

Magnus Starkhammar; Susanna Kumlien Georén; Linda Swedin; Sven-Erik Dahlén; Mikael Adner; Lars Olaf Cardell

doi:10.1371/journal.pone.0032110

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Peer-reviewed

Research Article

Intranasal Administration of poly(I:C) and LPS in BALB/c Mice Induces Airway Hyperresponsiveness and Inflammation via Different Pathways

Magnus Starkhammar,

Affiliations Division of ENT Diseases, CLINTEC, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, Unit for Experimental Asthma and Allergy Research, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
⨯
Susanna Kumlien Georén,

Affiliations Division of ENT Diseases, CLINTEC, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, Unit for Experimental Asthma and Allergy Research, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
⨯
Linda Swedin,

Affiliations Unit for Experimental Asthma and Allergy Research, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, The Centre for Allergy Reseach, Karolinska Institutet, Stockholm, Sweden
⨯
Sven-Erik Dahlén,

Affiliations Unit for Experimental Asthma and Allergy Research, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, The Centre for Allergy Reseach, Karolinska Institutet, Stockholm, Sweden
⨯
Mikael Adner,

Affiliations Unit for Experimental Asthma and Allergy Research, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, The Centre for Allergy Reseach, Karolinska Institutet, Stockholm, Sweden
⨯
Lars Olaf Cardell

* E-mail: lars-olaf.cardell@ki.se

Affiliations Division of ENT Diseases, CLINTEC, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, The Centre for Allergy Reseach, Karolinska Institutet, Stockholm, Sweden
⨯

Intranasal Administration of poly(I:C) and LPS in BALB/c Mice Induces Airway Hyperresponsiveness and Inflammation via Different Pathways

Magnus Starkhammar,
Susanna Kumlien Georén,
Linda Swedin,
Sven-Erik Dahlén,
Mikael Adner,
Lars Olaf Cardell

Published: February 15, 2012
https://doi.org/10.1371/journal.pone.0032110

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