Urokinase Plasminogen Receptor and the Fibrinolytic Complex Play a Role in Nerve Repair after Nerve Crush in Mice, and in Human Neuropathies

Cristina Rivellini; Giorgia Dina; Emanuela Porrello; Federica Cerri; Marina Scarlato; Teuta Domi; Daniela Ungaro; Ubaldo Del Carro; Alessandra Bolino; Angelo Quattrini; Giancarlo Comi; Stefano C. Previtali

doi:10.1371/journal.pone.0032059

Loading metrics

Open Access

Peer-reviewed

Research Article

Urokinase Plasminogen Receptor and the Fibrinolytic Complex Play a Role in Nerve Repair after Nerve Crush in Mice, and in Human Neuropathies

Cristina Rivellini,

Affiliations Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy
⨯
Giorgia Dina,

Affiliations Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy
⨯
Emanuela Porrello,

Affiliations Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy
⨯
Federica Cerri,

Affiliations Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy, Department of Neurology, San Raffaele Scientific Institute, Milan, Italy
⨯
Marina Scarlato,

Affiliations Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy, Department of Neurology, San Raffaele Scientific Institute, Milan, Italy
⨯
Teuta Domi,

Affiliations Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy
⨯
Daniela Ungaro,

Affiliation Department of Neurology, San Raffaele Scientific Institute, Milan, Italy
⨯
Ubaldo Del Carro,

Affiliation Department of Neurology, San Raffaele Scientific Institute, Milan, Italy
⨯
Alessandra Bolino,

Affiliations Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy, Dulbecco Telethon Institute, Rome, Italy
⨯
Angelo Quattrini,

Affiliations Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy, Department of Neurology, San Raffaele Scientific Institute, Milan, Italy
⨯
Giancarlo Comi,

Affiliations Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy, Department of Neurology, San Raffaele Scientific Institute, Milan, Italy, “Vita e Salute” San Raffaele University, Milan, Italy
⨯
Stefano C. Previtali

* E-mail: previtali.stefano@hsr.it

Affiliations Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy, Department of Neurology, San Raffaele Scientific Institute, Milan, Italy
⨯

Urokinase Plasminogen Receptor and the Fibrinolytic Complex Play a Role in Nerve Repair after Nerve Crush in Mice, and in Human Neuropathies

Cristina Rivellini,
Giorgia Dina,
Emanuela Porrello,
Federica Cerri,
Marina Scarlato,
Teuta Domi,
Daniela Ungaro,
Ubaldo Del Carro,
Alessandra Bolino,
Angelo Quattrini

Published: February 21, 2012
https://doi.org/10.1371/journal.pone.0032059

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Nerve regeneration
Is the Subject Area "Nerve regeneration" applicable to this article?

Thanks for your feedback.
Fibrin
Is the Subject Area "Fibrin" applicable to this article?

Thanks for your feedback.
Sciatic nerves
Is the Subject Area "Sciatic nerves" applicable to this article?

Thanks for your feedback.
Neuropathy
Is the Subject Area "Neuropathy" applicable to this article?

Thanks for your feedback.
Nerve fibers
Is the Subject Area "Nerve fibers" applicable to this article?

Thanks for your feedback.
Nerves
Is the Subject Area "Nerves" applicable to this article?

Thanks for your feedback.
Fibrinolysis
Is the Subject Area "Fibrinolysis" applicable to this article?

Thanks for your feedback.
Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.