Dynamic Network of Transcription and Pathway Crosstalk to Reveal Molecular Mechanism of MGd-Treated Human Lung Cancer Cells

Liyan Shao; Lishan Wang; Zhiyun Wei; Yuyu Xiong; Yang Wang; Kefu Tang; Yang Li; Guoyin Feng; Qinghe Xing; Lin He

doi:10.1371/journal.pone.0031984

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Open Access

Peer-reviewed

Research Article

Dynamic Network of Transcription and Pathway Crosstalk to Reveal Molecular Mechanism of MGd-Treated Human Lung Cancer Cells

Liyan Shao ,

Contributed equally to this work with: Liyan Shao, Lishan Wang

Affiliation Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China
⨯
Lishan Wang ,

Contributed equally to this work with: Liyan Shao, Lishan Wang

Affiliation Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China
⨯
Zhiyun Wei,

Affiliation Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China
⨯
Yuyu Xiong,

Affiliation Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China
⨯
Yang Wang,

Affiliation Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China
⨯
Kefu Tang,

Affiliation Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China
⨯
Yang Li,

Affiliation Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China
⨯
Guoyin Feng,

Affiliation Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China
⨯
Qinghe Xing ,

* E-mail: xingqinghesjtu@gmail.com (QX); helin@bio-x.cn (LH)

Affiliation Institutes of Biomedical Sciences, Fudan University, Shanghai, China
⨯
Lin He

* E-mail: xingqinghesjtu@gmail.com (QX); helin@bio-x.cn (LH)

Affiliations Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China, Institute for Nutritional Sciences, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai, China, Institutes of Biomedical Sciences, Fudan University, Shanghai, China
⨯

Dynamic Network of Transcription and Pathway Crosstalk to Reveal Molecular Mechanism of MGd-Treated Human Lung Cancer Cells

Liyan Shao,
Lishan Wang,
Zhiyun Wei,
Yuyu Xiong,
Yang Wang,
Kefu Tang,
Yang Li,
Guoyin Feng,
Qinghe Xing,
Lin He

Published: May 31, 2012
https://doi.org/10.1371/journal.pone.0031984

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Gene expression
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Lung and intrathoracic tumors
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Transcription factors
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Gene regulation
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Transcriptional control
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PPAR signaling
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Non-small cell lung cancer
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