Novel Information on the Epitope of an Inverse Agonist Monoclonal Antibody Provides Insight into the Structure of the TSH Receptor

Open Access

Peer-reviewed

Research Article

Chun-Rong Chen,

Affiliations Thyroid Autoimmune Disease Unit, Cedars-Sinai Medical Center, Los Angeles, California, United States of America, University of California Los Angeles School of Medicine, Los Angeles, California, United States of America
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Larry M. Salazar,

Affiliation Thyroid Autoimmune Disease Unit, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
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Sandra M. McLachlan,

Affiliations Thyroid Autoimmune Disease Unit, Cedars-Sinai Medical Center, Los Angeles, California, United States of America, University of California Los Angeles School of Medicine, Los Angeles, California, United States of America
⨯
Basil Rapoport

* E-mail: rapoportb@cshs.org

Affiliations Thyroid Autoimmune Disease Unit, Cedars-Sinai Medical Center, Los Angeles, California, United States of America, University of California Los Angeles School of Medicine, Los Angeles, California, United States of America
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Alanine
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Crystal structure
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Substitution mutation
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CHO cells
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Signal transduction
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Cell membranes
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Monoclonal antibodies
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Transmembrane receptors
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