Loss of Secreted Frizzled-Related Protein 4 Correlates with an Aggressive Phenotype and Predicts Poor Outcome in Ovarian Cancer Patients

• Francis Jacob ,

  Contributed equally to this work with: Francis Jacob, Kristjan Ukegjini

  Affiliations Translational Research Group, University Hospital Zurich, Zurich, Switzerland, Gynaecological Cancer Group, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia

  ⨯
• Kristjan Ukegjini ,

  Contributed equally to this work with: Francis Jacob, Kristjan Ukegjini

  Affiliation Translational Research Group, University Hospital Zurich, Zurich, Switzerland

  ⨯
• Sheri Nixdorf,

  Affiliation Gynaecological Cancer Group, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia

  ⨯
• Caroline E. Ford,

  Affiliation Wnt signaling and Metastasis Group, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia

  ⨯
• Jake Olivier,

  Affiliation Biostatistics Group, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia

  ⨯
• Rosmarie Caduff,

  Affiliation Institute of Clinical Pathology, University Hospital Zurich, Zurich, Switzerland

  ⨯
• James P. Scurry,

  Affiliation Hunter Area Pathology Services, John Hunter Hospital, University of Newcastle, Callaghan, Australia

  ⨯
• Rea Guertler,

  Affiliation Gynaecological Cancer Group, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia

  ⨯
• Daniela Hornung,

  Affiliation Department of Obstetrics and Gynecology, University of Schleswig-Holstein, Lubeck, Germany

  ⨯
• Renato Mueller,

  Affiliation Department of Gynecology and Obstetrics, Spital Limmattal, Zurich, Switzerland

  ⨯
• Daniel A. Fink,

  Affiliation Department of Gynecology, University Hospital Zurich, Zurich, Switzerland

  ⨯
• Neville F. Hacker,

  Affiliation Gynaecological Cancer Centre, Royal Hospital for Women, Sydney, Australia

  ⨯
• Viola A. Heinzelmann-Schwarz

  * E-mail: viola@heinzelmann.ch

  Affiliations Translational Research Group, University Hospital Zurich, Zurich, Switzerland, Gynaecological Cancer Group, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia, Gynaecological Cancer Centre, Royal Hospital for Women, Sydney, Australia

  ⨯