Maternal Obesity Enhances Collagen Accumulation and Cross-Linking in Skeletal Muscle of Ovine Offspring

Yan Huang; Jun-Xing Zhao; Xu Yan; Mei-Jun Zhu; Nathan M. Long; Richard J. McCormick; Stephen P. Ford; Peter W. Nathanielsz; Min Du

doi:10.1371/journal.pone.0031691

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Peer-reviewed

Research Article

Maternal Obesity Enhances Collagen Accumulation and Cross-Linking in Skeletal Muscle of Ovine Offspring

Yan Huang,

Affiliation Developmental Biology Group, Department of Animal Science, Center for the Study of Fetal Programming, University of Wyoming, Laramie, Wyoming, United States of America
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Jun-Xing Zhao,

Affiliation Developmental Biology Group, Department of Animal Science, Center for the Study of Fetal Programming, University of Wyoming, Laramie, Wyoming, United States of America
⨯
Xu Yan,

Affiliation Developmental Biology Group, Department of Animal Science, Center for the Study of Fetal Programming, University of Wyoming, Laramie, Wyoming, United States of America
⨯
Mei-Jun Zhu,

Affiliation Developmental Biology Group, Department of Animal Science, Center for the Study of Fetal Programming, University of Wyoming, Laramie, Wyoming, United States of America
⨯
Nathan M. Long,

Affiliation Developmental Biology Group, Department of Animal Science, Center for the Study of Fetal Programming, University of Wyoming, Laramie, Wyoming, United States of America
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Richard J. McCormick,

Affiliation Developmental Biology Group, Department of Animal Science, Center for the Study of Fetal Programming, University of Wyoming, Laramie, Wyoming, United States of America
⨯
Stephen P. Ford,

Affiliation Developmental Biology Group, Department of Animal Science, Center for the Study of Fetal Programming, University of Wyoming, Laramie, Wyoming, United States of America
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Peter W. Nathanielsz,

Affiliation Center for Pregnancy and Newborn Research, Health Sciences Center, University of Texas, San Antonio, Texas, United States of America
⨯
Min Du

* E-mail: min.du@wsu.edu

Affiliations Developmental Biology Group, Department of Animal Science, Center for the Study of Fetal Programming, University of Wyoming, Laramie, Wyoming, United States of America, Department of Animal Sciences, Washington State University, Pullman, Washington, United States of America
⨯

Maternal Obesity Enhances Collagen Accumulation and Cross-Linking in Skeletal Muscle of Ovine Offspring

Yan Huang,
Jun-Xing Zhao,
Xu Yan,
Mei-Jun Zhu,
Nathan M. Long,
Richard J. McCormick,
Stephen P. Ford,
Peter W. Nathanielsz,
Min Du

Published: February 14, 2012
https://doi.org/10.1371/journal.pone.0031691

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Collagens
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Skeletal muscles
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Slow-twitch muscle fibers
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Obesity
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Cross-linking
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Body weight
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Fibrosis
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