Homocysteinylated Albumin Promotes Increased Monocyte-Endothelial Cell Adhesion and Up-Regulation of MCP1, Hsp60 and ADAM17

Rosanna Capasso; Irene Sambri; Amelia Cimmino; Sofia Salemme; Cinzia Lombardi; Filomena Acanfora; Ersilia Satta; Donald L. Puppione; Alessandra F. Perna; Diego Ingrosso

doi:10.1371/journal.pone.0031388

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Peer-reviewed

Research Article

Homocysteinylated Albumin Promotes Increased Monocyte-Endothelial Cell Adhesion and Up-Regulation of MCP1, Hsp60 and ADAM17

Rosanna Capasso,

Affiliation Department of Biochemistry and Biophysics “F. Cedrangolo”, School of Medicine, Second University of Naples, Naples, Italy
⨯
Irene Sambri,

Affiliation Department of Biochemistry and Biophysics “F. Cedrangolo”, School of Medicine, Second University of Naples, Naples, Italy
⨯
Amelia Cimmino,

Affiliation Institute of Genetics and Biophysics, National Research Council, Naples, Italy
⨯
Sofia Salemme,

Affiliation Department of Biochemistry and Biophysics “F. Cedrangolo”, School of Medicine, Second University of Naples, Naples, Italy
⨯
Cinzia Lombardi,

Affiliation First Division of Nephrology, School of Medicine, Second University of Naples, Naples, Italy
⨯
Filomena Acanfora,

Affiliation First Division of Nephrology, School of Medicine, Second University of Naples, Naples, Italy
⨯
Ersilia Satta,

Affiliation First Division of Nephrology, School of Medicine, Second University of Naples, Naples, Italy
⨯
Donald L. Puppione,

Affiliation The Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America
⨯
Alessandra F. Perna ,

* E-mail: alessandra.perna@unina2.it

Affiliations Cardiovascular Research Centre, School of Medicine, Second University of Naples, Naples, Italy, First Division of Nephrology, School of Medicine, Second University of Naples, Naples, Italy
⨯
Diego Ingrosso

Affiliations Department of Biochemistry and Biophysics “F. Cedrangolo”, School of Medicine, Second University of Naples, Naples, Italy, Cardiovascular Research Centre, School of Medicine, Second University of Naples, Naples, Italy
⨯

Homocysteinylated Albumin Promotes Increased Monocyte-Endothelial Cell Adhesion and Up-Regulation of MCP1, Hsp60 and ADAM17

Rosanna Capasso,
Irene Sambri,
Amelia Cimmino,
Sofia Salemme,
Cinzia Lombardi,
Filomena Acanfora,
Ersilia Satta,
Donald L. Puppione,
Alessandra F. Perna,
Diego Ingrosso

Published: February 3, 2012
https://doi.org/10.1371/journal.pone.0031388

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Albumins
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Monocytes
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Endothelial cells
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Electrospray ionization mass spectrometry
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Serum albumin
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Gene expression
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Cell adhesion
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Enzyme-linked immunoassays
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