A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity

• Patrick Ymele-Leki,

  Affiliation Division of Infectious Diseases, Children's Hospital, Boston, Boston, Massachusetts, United States of America

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• Shugeng Cao,

  Affiliation Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts, United States of America

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• Jared Sharp,

  Affiliation Division of Infectious Diseases, Children's Hospital, Boston, Boston, Massachusetts, United States of America

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• Kathleen G. Lambert,

  Affiliation Department of Laboratory Medicine, Children's Hospital, Boston, Boston, Massachusetts, United States of America

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• Alexander J. McAdam,

  Affiliation Department of Laboratory Medicine, Children's Hospital, Boston, Boston, Massachusetts, United States of America

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• Robert N. Husson,

  Affiliation Division of Infectious Diseases, Children's Hospital, Boston, Boston, Massachusetts, United States of America

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• Giselle Tamayo,

  Affiliation Unidad Estrategica de Bioprospeccion, Instituto Nacional de Biodiversidad (INBio) and Escuela de Química, Universidad de Costa Rica, San José, Costa Rica

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• Jon Clardy,

  Affiliation Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts, United States of America

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• Paula I. Watnick

  * E-mail: paula.watnick@childrens.harvard.edu

  Affiliation Division of Infectious Diseases, Children's Hospital, Boston, Boston, Massachusetts, United States of America

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