Redirecting T Cells to Ewing's Sarcoma Family of Tumors by a Chimeric NKG2D Receptor Expressed by Lentiviral Transduction or mRNA Transfection

Manfred Lehner; Gabriel Götz; Julia Proff; Niels Schaft; Jan Dörrie; Florian Full; Armin Ensser; Yves A. Muller; Adelheid Cerwenka; Hinrich Abken; Ornella Parolini; Peter F. Ambros; Heinrich Kovar; Wolfgang Holter

doi:10.1371/journal.pone.0031210

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Peer-reviewed

Research Article

Redirecting T Cells to Ewing's Sarcoma Family of Tumors by a Chimeric NKG2D Receptor Expressed by Lentiviral Transduction or mRNA Transfection

Manfred Lehner ,

Contributed equally to this work with: Manfred Lehner, Gabriel Götz

* E-mail: manfred.lehner@uk-erlangen.de

Affiliation Laboratory of Cellular Therapy, Children's University Hospital, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Gabriel Götz ,

Contributed equally to this work with: Manfred Lehner, Gabriel Götz

Affiliation Laboratory of Cellular Therapy, Children's University Hospital, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Julia Proff,

Affiliation Laboratory of Cellular Therapy, Children's University Hospital, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Niels Schaft,

Affiliation Department of Dermatology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Jan Dörrie,

Affiliation Department of Dermatology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Florian Full,

Affiliation Institute for Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Armin Ensser,

Affiliation Institute for Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Yves A. Muller,

Affiliation Lehrstuhl für Biotechnik, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Adelheid Cerwenka,

Affiliation German Cancer Research Center, Heidelberg, Germany
⨯
Hinrich Abken,

Affiliation Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany
⨯
Ornella Parolini,

Affiliation Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy
⨯
Peter F. Ambros,

Affiliation Children's Cancer Research Institute (CCRI), St. Anna Hospital, Vienna, Austria
⨯
Heinrich Kovar,

Affiliation Children's Cancer Research Institute (CCRI), St. Anna Hospital, Vienna, Austria
⨯
Wolfgang Holter

Affiliation Laboratory of Cellular Therapy, Children's University Hospital, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯

Redirecting T Cells to Ewing's Sarcoma Family of Tumors by a Chimeric NKG2D Receptor Expressed by Lentiviral Transduction or mRNA Transfection

Manfred Lehner,
Gabriel Götz,
Julia Proff,
Niels Schaft,
Jan Dörrie,
Florian Full,
Armin Ensser,
Yves A. Muller,
Adelheid Cerwenka,
Hinrich Abken

Published: February 15, 2012
https://doi.org/10.1371/journal.pone.0031210

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07 Jun 2012
21:07 GMT
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Publisher's Note: Figure 5 (D-E) missing. Posted by PLOS_ONE_Group on 07 Jun 2012 at 21:07 GMT

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