Activation of CD40 with Platelet Derived CD154 Promotes Reactive Oxygen Species Dependent Death of Human Hepatocytes during Hypoxia and Reoxygenation

Open Access

Peer-reviewed

Research Article

Ricky H. Bhogal ,

* E-mail: balsin@hotmail.com

Affiliation Centre for Liver Research, School of Infection and Immunity, Institute of Biomedical Research, The Medical School, The University of Birmingham, Edgbaston, Birmingham, United Kingdom
⨯
Christopher J. Weston,

Affiliation Centre for Liver Research, School of Infection and Immunity, Institute of Biomedical Research, The Medical School, The University of Birmingham, Edgbaston, Birmingham, United Kingdom
⨯
Stuart M. Curbishley,

Affiliation Centre for Liver Research, School of Infection and Immunity, Institute of Biomedical Research, The Medical School, The University of Birmingham, Edgbaston, Birmingham, United Kingdom
⨯
David H. Adams,

Affiliation Centre for Liver Research, School of Infection and Immunity, Institute of Biomedical Research, The Medical School, The University of Birmingham, Edgbaston, Birmingham, United Kingdom
⨯
Simon C. Afford

Affiliation Centre for Liver Research, School of Infection and Immunity, Institute of Biomedical Research, The Medical School, The University of Birmingham, Edgbaston, Birmingham, United Kingdom
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Hepatocytes
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Apoptosis
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Hypoxia
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Necrosis
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Medical hypoxia
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Necrotic cell death
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Platelet activation
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Flow cytometry
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