CD8+ T Cells Mediate the Athero-Protective Effect of Immunization with an ApoB-100 Peptide

Kuang-Yuh Chyu; Xiaoning Zhao; Paul C. Dimayuga; Jianchang Zhou; Xiaojun Li; Juliana Yano; Wai Man Lio; Lai Fan Chan; Jonathan Kirzner; Portia Trinidad; Bojan Cercek; Prediman K. Shah

doi:10.1371/journal.pone.0030780

Loading metrics

Open Access

Peer-reviewed

Research Article

CD8⁺ T Cells Mediate the Athero-Protective Effect of Immunization with an ApoB-100 Peptide

Kuang-Yuh Chyu ,

Contributed equally to this work with: Kuang-Yuh Chyu, Xiaoning Zhao

Affiliation Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Xiaoning Zhao ,

Contributed equally to this work with: Kuang-Yuh Chyu, Xiaoning Zhao

Affiliation Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Paul C. Dimayuga,

Affiliation Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Jianchang Zhou,

Affiliation Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Xiaojun Li,

Affiliation Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Juliana Yano,

Affiliation Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Wai Man Lio,

Affiliation Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Lai Fan Chan,

Affiliation Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Jonathan Kirzner,

Affiliation Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Portia Trinidad,

Affiliation Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Bojan Cercek,

Affiliation Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Prediman K. Shah

* E-mail: ShahP@cshs.org

Affiliation Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯

CD8⁺ T Cells Mediate the Athero-Protective Effect of Immunization with an ApoB-100 Peptide

Kuang-Yuh Chyu,
Xiaoning Zhao,
Paul C. Dimayuga,
Jianchang Zhou,
Xiaojun Li,
Juliana Yano,
Wai Man Lio,
Lai Fan Chan,
Jonathan Kirzner,
Portia Trinidad

Published: February 9, 2012
https://doi.org/10.1371/journal.pone.0030780

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Atherosclerosis
Is the Subject Area "Atherosclerosis" applicable to this article?

Thanks for your feedback.
Immune response
Is the Subject Area "Immune response" applicable to this article?

Thanks for your feedback.
Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.
Dendritic cells
Is the Subject Area "Dendritic cells" applicable to this article?

Thanks for your feedback.
Antibody response
Is the Subject Area "Antibody response" applicable to this article?

Thanks for your feedback.
Euthanasia
Is the Subject Area "Euthanasia" applicable to this article?

Thanks for your feedback.