Copper Deficiency Induced Emphysema Is Associated with Focal Adhesion Kinase Inactivation

Shiro Mizuno; Masanori Yasuo; Harm J. Bogaard; Donatas Kraskauskas; Aysar Alhussaini; Jose Gomez-Arroyo; Daniela Farkas; Laszlo Farkas; Norbert F. Voelkel

doi:10.1371/journal.pone.0030678

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Peer-reviewed

Research Article

Copper Deficiency Induced Emphysema Is Associated with Focal Adhesion Kinase Inactivation

Shiro Mizuno,

Affiliations Pulmonary and Critical Care Medicine Division and Victoria Johnson Center for Obstructive Lung Diseases, Virginia Commonwealth University, Richmond, Virginia, United States of America, Division of Respiratory Disease, Kanazawa Medical University, Ishikawa, Japan
⨯
Masanori Yasuo,

Affiliation Pulmonary and Critical Care Medicine Division and Victoria Johnson Center for Obstructive Lung Diseases, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Harm J. Bogaard,

Affiliation VU University Medical Center, Amsterdam, The Netherlands
⨯
Donatas Kraskauskas,

Affiliation Pulmonary and Critical Care Medicine Division and Victoria Johnson Center for Obstructive Lung Diseases, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Aysar Alhussaini,

Affiliation Pulmonary and Critical Care Medicine Division and Victoria Johnson Center for Obstructive Lung Diseases, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Jose Gomez-Arroyo,

Affiliation Pulmonary and Critical Care Medicine Division and Victoria Johnson Center for Obstructive Lung Diseases, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Daniela Farkas,

Affiliation Pulmonary and Critical Care Medicine Division and Victoria Johnson Center for Obstructive Lung Diseases, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Laszlo Farkas,

Affiliation Pulmonary and Critical Care Medicine Division and Victoria Johnson Center for Obstructive Lung Diseases, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Norbert F. Voelkel

* E-mail: nvoelkel@mcvh-vcu.edu

Affiliation Pulmonary and Critical Care Medicine Division and Victoria Johnson Center for Obstructive Lung Diseases, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯

Copper Deficiency Induced Emphysema Is Associated with Focal Adhesion Kinase Inactivation

Shiro Mizuno,
Masanori Yasuo,
Harm J. Bogaard,
Donatas Kraskauskas,
Aysar Alhussaini,
Jose Gomez-Arroyo,
Daniela Farkas,
Laszlo Farkas,
Norbert F. Voelkel

Published: January 20, 2012
https://doi.org/10.1371/journal.pone.0030678

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Protein expression
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Emphysema
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Small interfering RNA
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Protein extraction
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Gene expression
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Micronutrient deficiencies
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DNA-binding proteins
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