Increased Expression of PcG Protein YY1 Negatively Regulates B Cell Development while Allowing Accumulation of Myeloid Cells and LT-HSC Cells

Open Access

Peer-reviewed

Research Article

Xuan Pan,

Affiliation Department of Animal Biology, School of Veterinary, University of Pennsylvania, Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Morgan Jones,

Affiliation Center for Stem Cell Biology, Life Sciences Institute, Departments of Medicine & Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Jie Jiang,

Affiliation Department of Animal Biology, School of Veterinary, University of Pennsylvania, Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Kristina Zaprazna,

Affiliation Department of Animal Biology, School of Veterinary, University of Pennsylvania, Medicine, Philadelphia, Pennsylvania, United States of America
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Duonan Yu,

Affiliation Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Warren Pear,

Affiliation Department of Pathology and Laboratory Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Ivan Maillard,

Affiliation Center for Stem Cell Biology, Life Sciences Institute, Departments of Medicine & Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Michael L. Atchison

* E-mail: atchison@vet.upenn.edu

Affiliation Department of Animal Biology, School of Veterinary, University of Pennsylvania, Medicine, Philadelphia, Pennsylvania, United States of America
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B cells
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Bone marrow cells
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Apoptosis
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DNA-binding proteins
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Hematopoietic stem cells
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Gene regulation
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Flow cytometry
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Transcription factors
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