Type II NKT Cells Stimulate Diet-Induced Obesity by Mediating Adipose Tissue Inflammation, Steatohepatitis and Insulin Resistance

• Masashi Satoh ,

  Contributed equally to this work with: Masashi Satoh, Yasuhiro Andoh

  Affiliations Department of Immunology, Kitasato University School of Medicine, Sagamihar, Japan, Division of Immunobiology, Research Section of Pathophysiology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

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• Yasuhiro Andoh ,

  Contributed equally to this work with: Masashi Satoh, Yasuhiro Andoh

  Affiliations Division of Immunobiology, Research Section of Pathophysiology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan, Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan

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• Christopher Stuart Clingan,

  Affiliations Division of Immunobiology, Research Section of Pathophysiology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan, Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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• Hisako Ogura,

  Affiliation Division of Immunobiology, Research Section of Pathophysiology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

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• Satoshi Fujii,

  Affiliation Department of Molecular and Cellular Pathobiology and Therapeutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan

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• Koji Eshima,

  Affiliation Department of Immunology, Kitasato University School of Medicine, Sagamihar, Japan

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• Toshinori Nakayama,

  Affiliation Department of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Masaru Taniguchi,

  Affiliation RIKEN Research Center for Allergy and Immunology, Yokohama, Japan

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• Noriyuki Hirata,

  Affiliations Division of Immunobiology, Research Section of Pathophysiology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan, Division of Cancer Biology, Research Section of Pathophysiology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

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• Naoki Ishimori,

  Affiliation Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan

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• Hiroyuki Tsutsui,

  Affiliation Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan

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• Kazunori Onoé,

  Affiliation Division of Immunobiology, Research Section of Pathophysiology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

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• Kazuya Iwabuchi

  * E-mail: akimari@kitasato-u.ac.jp

  Affiliations Department of Immunology, Kitasato University School of Medicine, Sagamihar, Japan, Division of Immunobiology, Research Section of Pathophysiology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

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