Presenilin Is the Molecular Target of Acidic γ-Secretase Modulators in Living Cells

• Thorsten Jumpertz ,

  Contributed equally to this work with: Thorsten Jumpertz, Andreas Rennhack

  Affiliation Department of Neuropathology, Heinrich-Heine-University, Duesseldorf, Germany

  ⨯
• Andreas Rennhack ,

  Contributed equally to this work with: Thorsten Jumpertz, Andreas Rennhack

  Affiliation Research Group Chemical Biology of Neurodegenerative Diseases, Center of Advanced European Studies and Research, Bonn, Germany

  ⨯
• Julia Ness,

  Affiliation Department of Neuropathology, Heinrich-Heine-University, Duesseldorf, Germany

  ⨯
• Sandra Baches,

  Affiliation Department of Neuropathology, Heinrich-Heine-University, Duesseldorf, Germany

  ⨯
• Claus U. Pietrzik,

  Affiliation Molecular Neurodegeneration Group, Institute of Pathobiochemistry, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany

  ⨯
• Bruno Bulic ,

  * E-mail: bruno.bulic@caesar.de (BB); sweggen@uni-duesseldorf.de (SW)

  Affiliation Research Group Chemical Biology of Neurodegenerative Diseases, Center of Advanced European Studies and Research, Bonn, Germany

  ⨯
• Sascha Weggen

  * E-mail: bruno.bulic@caesar.de (BB); sweggen@uni-duesseldorf.de (SW)

  Affiliation Department of Neuropathology, Heinrich-Heine-University, Duesseldorf, Germany

  ⨯