HIF-Independent Regulation of Thioredoxin Reductase 1 Contributes to the High Levels of Reactive Oxygen Species Induced by Hypoxia

Open Access

Peer-reviewed

Research Article

Salvador Naranjo-Suarez,

Affiliations Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, United States of America, Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Bradley A. Carlson,

Affiliation Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, United States of America
⨯
Petra A. Tsuji,

Affiliations Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, United States of America, Department of Biological Sciences, Towson University, Towson, Maryland, United States of America
⨯
Min-Hyuk Yoo,

Affiliation Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, United States of America
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Vadim N. Gladyshev,

Affiliation Division of Genetics, Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Dolph L. Hatfield

* E-mail: hatfield@mail.nih.gov

Affiliation Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, United States of America
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Hypoxia
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Medical hypoxia
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Gene expression
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Retroviruses
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Aquatic hypoxia
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Reactive oxygen species
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Transcription factors
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Mitochondria
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