Signaling Networks Associated with AKT Activation in Non-Small Cell Lung Cancer (NSCLC): New Insights on the Role of Phosphatydil-Inositol-3 kinase

Marianna Scrima; Carmela De Marco; Fernanda Fabiani; Renato Franco; Giuseppe Pirozzi; Gaetano Rocco; Maria Ravo; Alessandro Weisz; Pietro Zoppoli; Michele Ceccarelli; Gerardo Botti; Donatella Malanga; Giuseppe Viglietto

doi:10.1371/journal.pone.0030427

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Open Access

Peer-reviewed

Research Article

Signaling Networks Associated with AKT Activation in Non-Small Cell Lung Cancer (NSCLC): New Insights on the Role of Phosphatydil-Inositol-3 kinase

Marianna Scrima,

Affiliation Biogem scarl, Institute for Genetic Research “Gaetano Salvatore”, Ariano Irpino (Avellino), Italy
⨯
Carmela De Marco,

Affiliations Biogem scarl, Institute for Genetic Research “Gaetano Salvatore”, Ariano Irpino (Avellino), Italy, Department of Experimental and Clinical Medicine, University Magna Graecia Catanzaro, Italy
⨯
Fernanda Fabiani,

Affiliation Department of Experimental and Clinical Medicine, University Magna Graecia Catanzaro, Italy
⨯
Renato Franco,

Affiliation Fondazione “G Pascale”, National Cancer Institute, Naples, Italy
⨯
Giuseppe Pirozzi,

Affiliation Fondazione “G Pascale”, National Cancer Institute, Naples, Italy
⨯
Gaetano Rocco,

Affiliation Fondazione “G Pascale”, National Cancer Institute, Naples, Italy
⨯
Maria Ravo,

Affiliation Molecular Medicine Laboratory, Faculty of Medicine and Surgery, University of Salerno, Baronissi, Italy
⨯
Alessandro Weisz,

Affiliation Molecular Medicine Laboratory, Faculty of Medicine and Surgery, University of Salerno, Baronissi, Italy
⨯
Pietro Zoppoli,

Affiliations Biogem scarl, Institute for Genetic Research “Gaetano Salvatore”, Ariano Irpino (Avellino), Italy, Department of Biological and Environmental Studies, University of Sannio, Benevento, Italy
⨯
Michele Ceccarelli,

Affiliations Biogem scarl, Institute for Genetic Research “Gaetano Salvatore”, Ariano Irpino (Avellino), Italy, Department of Biological and Environmental Studies, University of Sannio, Benevento, Italy
⨯
Gerardo Botti,

Affiliation Fondazione “G Pascale”, National Cancer Institute, Naples, Italy
⨯
Donatella Malanga,

Affiliations Biogem scarl, Institute for Genetic Research “Gaetano Salvatore”, Ariano Irpino (Avellino), Italy, Department of Experimental and Clinical Medicine, University Magna Graecia Catanzaro, Italy
⨯
Giuseppe Viglietto

* E-mail: viglietto@unicz.it

Affiliations Biogem scarl, Institute for Genetic Research “Gaetano Salvatore”, Ariano Irpino (Avellino), Italy, Department of Experimental and Clinical Medicine, University Magna Graecia Catanzaro, Italy
⨯

Signaling Networks Associated with AKT Activation in Non-Small Cell Lung Cancer (NSCLC): New Insights on the Role of Phosphatydil-Inositol-3 kinase

Marianna Scrima,
Carmela De Marco,
Fernanda Fabiani,
Renato Franco,
Giuseppe Pirozzi,
Gaetano Rocco,
Maria Ravo,
Alessandro Weisz,
Pietro Zoppoli,
Michele Ceccarelli

Published: February 17, 2012
https://doi.org/10.1371/journal.pone.0030427

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Non-small cell lung cancer
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Cancers and neoplasms
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Lung and intrathoracic tumors
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Cell staining
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Oncogenic signaling
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Fluorescent in situ hybridization
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Gene expression
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Immunohistochemistry techniques
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