Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture

• Sarita Negi,

  Affiliations Human Islet Transplantation Laboratory, McGill University Health Centre, Montreal, Quebec, Canada, Department of Surgery, McGill University, Montreal, Quebec, Canada

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• Arif Jetha,

  Affiliations Human Islet Transplantation Laboratory, McGill University Health Centre, Montreal, Quebec, Canada, Department of Surgery, McGill University, Montreal, Quebec, Canada

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• Reid Aikin,

  Affiliations Human Islet Transplantation Laboratory, McGill University Health Centre, Montreal, Quebec, Canada, Department of Surgery, McGill University, Montreal, Quebec, Canada

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• Craig Hasilo,

  Affiliations Human Islet Transplantation Laboratory, McGill University Health Centre, Montreal, Quebec, Canada, Department of Surgery, McGill University, Montreal, Quebec, Canada

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• Rob Sladek,

  Affiliation McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada

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• Steven Paraskevas

  * E-mail: steven.paraskevas@mcgill.ca

  Affiliations Human Islet Transplantation Laboratory, McGill University Health Centre, Montreal, Quebec, Canada, Department of Surgery, McGill University, Montreal, Quebec, Canada

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