Interleukin-1 Receptor-Associated Kinase-3 Is a Key Inhibitor of Inflammation in Obesity and Metabolic Syndrome

Maarten Hulsmans; Benjamine Geeraert; Dieuwke De Keyzer; Ann Mertens; Matthias Lannoo; Bart Vanaudenaerde; Marc Hoylaerts; Nora Benhabilès; Christos Tsatsanis; Chantal Mathieu; Paul Holvoet

doi:10.1371/journal.pone.0030414

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Open Access

Peer-reviewed

Research Article

Interleukin-1 Receptor-Associated Kinase-3 Is a Key Inhibitor of Inflammation in Obesity and Metabolic Syndrome

Maarten Hulsmans ,

Contributed equally to this work with: Maarten Hulsmans, Benjamine Geeraert

Affiliation Atherosclerosis and Metabolism Unit, Department of Cardiovascular Diseases, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Benjamine Geeraert ,

Contributed equally to this work with: Maarten Hulsmans, Benjamine Geeraert

Affiliation Atherosclerosis and Metabolism Unit, Department of Cardiovascular Diseases, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Dieuwke De Keyzer,

Affiliation Atherosclerosis and Metabolism Unit, Department of Cardiovascular Diseases, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Ann Mertens,

Affiliation Experimental Medicine and Endocrinology Section, Department of Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Matthias Lannoo,

Affiliation Division of Abdominal Surgery, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Bart Vanaudenaerde,

Affiliation Pneumology Section, Department of Pathophysiology, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Marc Hoylaerts,

Affiliation Centre for Molecular and Vascular Biology, Department of Molecular and Cellular Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Nora Benhabilès,

Affiliation Atherosclerosis and Metabolism Unit, Department of Cardiovascular Diseases, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Christos Tsatsanis,

Affiliation Department of Clinical Chemistry, School of Medicine, University of Crete, Heraklion, Greece
⨯
Chantal Mathieu,

Affiliation Experimental Medicine and Endocrinology Section, Department of Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Paul Holvoet

* E-mail: paul.holvoet@med.kuleuven.be

Affiliation Atherosclerosis and Metabolism Unit, Department of Cardiovascular Diseases, Katholieke Universiteit Leuven, Leuven, Belgium
⨯

Interleukin-1 Receptor-Associated Kinase-3 Is a Key Inhibitor of Inflammation in Obesity and Metabolic Syndrome

Maarten Hulsmans,
Benjamine Geeraert,
Dieuwke De Keyzer,
Ann Mertens,
Matthias Lannoo,
Bart Vanaudenaerde,
Marc Hoylaerts,
Nora Benhabilès,
Christos Tsatsanis,
Chantal Mathieu

Published: January 17, 2012
https://doi.org/10.1371/journal.pone.0030414

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Obesity
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Adiponectin
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Monocytes
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Metabolic syndrome
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Glucose
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Weight loss
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