Interferon-Alpha Administration Enhances CD8+ T Cell Activation in HIV Infection

Maura Manion; Benigno Rodriguez; Kathleen Medvik; Gareth Hardy; Clifford V. Harding; Robert T. Schooley; Richard Pollard; David Asmuth; Robert Murphy; Edward Barker; Kirsten E. Brady; Alan Landay; Nick Funderburg; Scott F. Sieg; Michael M. Lederman

doi:10.1371/journal.pone.0030306

Loading metrics

Open Access

Peer-reviewed

Research Article

Interferon-Alpha Administration Enhances CD8+ T Cell Activation in HIV Infection

Maura Manion,

Affiliation Division of Infectious Diseases, Center for AIDS Research, Case Western Reserve University/University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯
Benigno Rodriguez,

Affiliation Division of Infectious Diseases, Center for AIDS Research, Case Western Reserve University/University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯
Kathleen Medvik,

Affiliation Division of Infectious Diseases, Center for AIDS Research, Case Western Reserve University/University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯
Gareth Hardy,

Affiliation Department of Pathology, Case Western Reserve University/University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯
Clifford V. Harding,

Affiliation Department of Pathology, Case Western Reserve University/University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯
Robert T. Schooley,

Affiliation Division of Infectious Diseases, University of California San Diego, La Jolla, California, United States of America
⨯
Richard Pollard,

Affiliation Division of Infectious Diseases, University of California Davis, Sacramento, California, United States of America
⨯
David Asmuth,

Affiliation Division of Infectious Diseases, University of California Davis, Sacramento, California, United States of America
⨯
Robert Murphy,

Affiliation Division of Infectious Diseases, Center for AIDS Research, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
⨯
Edward Barker,

Affiliation Department of Immunology and Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Kirsten E. Brady,

Affiliation Department of Immunology and Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Alan Landay,

Affiliation Department of Immunology and Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Nick Funderburg,

Affiliation Division of Infectious Diseases, Center for AIDS Research, Case Western Reserve University/University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯
Scott F. Sieg,

Affiliation Division of Infectious Diseases, Center for AIDS Research, Case Western Reserve University/University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯
Michael M. Lederman

* E-mail: lederman.michael@clevelandactu.org

Affiliation Division of Infectious Diseases, Center for AIDS Research, Case Western Reserve University/University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯

Interferon-Alpha Administration Enhances CD8+ T Cell Activation in HIV Infection

Maura Manion,
Benigno Rodriguez,
Kathleen Medvik,
Gareth Hardy,
Clifford V. Harding,
Robert T. Schooley,
Richard Pollard,
David Asmuth,
Robert Murphy,
Edward Barker

Published: January 24, 2012
https://doi.org/10.1371/journal.pone.0030306

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Interferons
Is the Subject Area "Interferons" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Genetic interference
Is the Subject Area "Genetic interference" applicable to this article?

Thanks for your feedback.
HIV infections
Is the Subject Area "HIV infections" applicable to this article?

Thanks for your feedback.
Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Immune activation
Is the Subject Area "Immune activation" applicable to this article?

Thanks for your feedback.
HIV
Is the Subject Area "HIV" applicable to this article?

Thanks for your feedback.
NK cells
Is the Subject Area "NK cells" applicable to this article?

Thanks for your feedback.