Reconsidering Association Testing Methods Using Single-Variant Test Statistics as Alternatives to Pooling Tests for Sequence Data with Rare Variants

Open Access

Peer-reviewed

Research Article

Daniel D. Kinnamon,

Affiliation Dr. John T. Macdonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America
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Ray E. Hershberger,

Affiliation Cardiovascular Division, Miller School of Medicine, University of Miami, Miami, Florida, United States of America
⨯
Eden R. Martin

* E-mail: emartin1@med.miami.edu

Affiliation Dr. John T. Macdonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America
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Medical risk factors
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Test statistics
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Alleles
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Variant genotypes
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Monte Carlo method
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