Novel Transgenic Mice for Inducible Gene Overexpression in Pancreatic Cells Define Glucocorticoid Receptor-Mediated Regulations of Beta Cells

Bertrand Blondeau; Iman Sahly; Emmanuelle Massouridès; Amrit Singh-Estivalet; Bérengère Valtat; Delphine Dorchene; Frédéric Jaisser; Bernadette Bréant; Francois Tronche

doi:10.1371/journal.pone.0030210

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Research Article

Novel Transgenic Mice for Inducible Gene Overexpression in Pancreatic Cells Define Glucocorticoid Receptor-Mediated Regulations of Beta Cells

Bertrand Blondeau ,

Contributed equally to this work with: Bertrand Blondeau, Iman Sahly

* E-mail: Bertrand.blondeau@crc.jussieu.fr

Affiliations INSERM UMR-S 872, Centre de Recherches des Cordeliers, Paris, France, Université Pierre et Marie Curie, Paris, France
⨯
Iman Sahly ,

Contributed equally to this work with: Bertrand Blondeau, Iman Sahly

Current address: Centre de Recherche Institut de la Vision, UMRS 968, Paris, France

Affiliations INSERM UMR-S 872, Centre de Recherches des Cordeliers, Paris, France, Université Pierre et Marie Curie, Paris, France
⨯
Emmanuelle Massouridès,

Affiliations Université Pierre et Marie Curie, Paris, France, Centre National de la Recherche Scientifique, UMR7224, “Molecular Genetics, Neurophysiology and Behavior” team, Paris, France, Institut National de la Santé et de la Recherche Médicale, U952, Paris, France
⨯
Amrit Singh-Estivalet,

Affiliations INSERM UMR-S 872, Centre de Recherches des Cordeliers, Paris, France, Université Pierre et Marie Curie, Paris, France
⨯
Bérengère Valtat,

Affiliations INSERM UMR-S 872, Centre de Recherches des Cordeliers, Paris, France, Université Pierre et Marie Curie, Paris, France
⨯
Delphine Dorchene,

Affiliations INSERM UMR-S 872, Centre de Recherches des Cordeliers, Paris, France, Université Pierre et Marie Curie, Paris, France
⨯
Frédéric Jaisser,

Affiliations INSERM UMR-S 872, Centre de Recherches des Cordeliers, Paris, France, Université Pierre et Marie Curie, Paris, France
⨯
Bernadette Bréant ,

¶These authors also contributed equally to this work.

Affiliations INSERM UMR-S 872, Centre de Recherches des Cordeliers, Paris, France, Université Pierre et Marie Curie, Paris, France
⨯
Francois Tronche

¶These authors also contributed equally to this work.

Affiliations Université Pierre et Marie Curie, Paris, France, Centre National de la Recherche Scientifique, UMR7224, “Molecular Genetics, Neurophysiology and Behavior” team, Paris, France, Institut National de la Santé et de la Recherche Médicale, U952, Paris, France
⨯

Novel Transgenic Mice for Inducible Gene Overexpression in Pancreatic Cells Define Glucocorticoid Receptor-Mediated Regulations of Beta Cells

Bertrand Blondeau,
Iman Sahly,
Emmanuelle Massouridès,
Amrit Singh-Estivalet,
Bérengère Valtat,
Delphine Dorchene,
Frédéric Jaisser,
Bernadette Bréant,
Francois Tronche

Published: February 17, 2012
https://doi.org/10.1371/journal.pone.0030210

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Genetically modified animals
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Pancreas
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Insulin
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