Remarkable Reduction of MAP2 in the Brains of Scrapie-Infected Rodents and Human Prion Disease Possibly Correlated with the Increase of Calpain

Yan Guo; Han-Shi Gong; Jin Zhang; Wu-Ling Xie; Chan Tian; Cao Chen; Qi Shi; Shao-Bin Wang; Yin Xu; Bao-Yun Zhang; Xiao-Ping Dong

doi:10.1371/journal.pone.0030163

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Open Access

Peer-reviewed

Research Article

Remarkable Reduction of MAP2 in the Brains of Scrapie-Infected Rodents and Human Prion Disease Possibly Correlated with the Increase of Calpain

Yan Guo,

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China
⨯
Han-Shi Gong,

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China
⨯
Jin Zhang ,

* E-mail: zhjoohyn@sina.com (JZ); dongxp238@sina.com (X-PD)

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China
⨯
Wu-Ling Xie,

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China
⨯
Chan Tian,

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China
⨯
Cao Chen,

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China
⨯
Qi Shi,

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China
⨯
Shao-Bin Wang,

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China
⨯
Yin Xu,

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China
⨯
Bao-Yun Zhang,

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China
⨯
Xiao-Ping Dong

* E-mail: zhjoohyn@sina.com (JZ); dongxp238@sina.com (X-PD)

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China
⨯

Remarkable Reduction of MAP2 in the Brains of Scrapie-Infected Rodents and Human Prion Disease Possibly Correlated with the Increase of Calpain

Yan Guo,
Han-Shi Gong,
Jin Zhang,
Wu-Ling Xie,
Chan Tian,
Cao Chen,
Qi Shi,
Shao-Bin Wang,
Yin Xu,
Bao-Yun Zhang

Published: January 17, 2012
https://doi.org/10.1371/journal.pone.0030163

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