CD40-Activated B Cells Can Efficiently Prime Antigen-Specific Naïve CD8+ T Cells to Generate Effector but Not Memory T cells

Open Access

Peer-reviewed

Research Article

CD40-Activated B Cells Can Efficiently Prime Antigen-Specific Naïve CD8⁺ T Cells to Generate Effector but Not Memory T cells

Mélissa Mathieu,

Affiliations Maisonneuve-Rosemont Hospital Research Center, Montréal, Québec, Canada, Department of Microbiology and Immunology, University of Montreal, Montréal, Québec, Canada
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Natacha Cotta-Grand,

Affiliations Maisonneuve-Rosemont Hospital Research Center, Montréal, Québec, Canada, Department of Microbiology and Immunology, University of Montreal, Montréal, Québec, Canada
⨯
Jean-François Daudelin,

Affiliation Maisonneuve-Rosemont Hospital Research Center, Montréal, Québec, Canada
⨯
Salix Boulet,

Affiliations Maisonneuve-Rosemont Hospital Research Center, Montréal, Québec, Canada, Department of Microbiology and Immunology, University of Montreal, Montréal, Québec, Canada
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Réjean Lapointe,

Affiliations Centre Hospitalier de l'Université de Montréal-Hôpital Notre-Dame Research Center (CRCHUM), Montréal, Québec, Canada, Department of Medicine, University of Montreal, Montréal, Québec, Canada
⨯
Nathalie Labrecque

* E-mail: nathalie.labrecque@umontreal.ca

Affiliations Maisonneuve-Rosemont Hospital Research Center, Montréal, Québec, Canada, Department of Microbiology and Immunology, University of Montreal, Montréal, Québec, Canada, Department of Medicine, University of Montreal, Montréal, Québec, Canada
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Cytotoxic T cells
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T cells
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Vaccination and immunization
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B cells
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Antigen-presenting cells
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Immune response
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Memory T cells
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Spleen
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