BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production

John E. S. Park; Dongmin Shao; Paul D. Upton; Patricia deSouza; Ian M. Adcock; Rachel J. Davies; Nicholas W. Morrell; Mark J. D. Griffiths; Stephen J. Wort

doi:10.1371/journal.pone.0030075

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Peer-reviewed

Research Article

BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production

John E. S. Park ,

Contributed equally to this work with: John E. S. Park, Dongmin Shao

Affiliation Unit of Critical Care, Royal Brompton Hospital, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Dongmin Shao ,

Contributed equally to this work with: John E. S. Park, Dongmin Shao

Affiliation Unit of Critical Care, Royal Brompton Hospital, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Paul D. Upton,

Affiliation Department of Medicine, School of Clinical Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom
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Patricia deSouza,

Affiliation Unit of Critical Care, Royal Brompton Hospital, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
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Ian M. Adcock,

Affiliation Airways Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
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Rachel J. Davies,

Affiliation Department of Medicine, School of Clinical Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom
⨯
Nicholas W. Morrell,

Affiliation Department of Medicine, School of Clinical Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom
⨯
Mark J. D. Griffiths ,

* E-mail: s.wort@imperial.ac.uk (SJW); m.griffiths@imperial.ac.uk (MJDG)

Affiliation Unit of Critical Care, Royal Brompton Hospital, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Stephen J. Wort

* E-mail: s.wort@imperial.ac.uk (SJW); m.griffiths@imperial.ac.uk (MJDG)

Affiliation Unit of Critical Care, Royal Brompton Hospital, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯

BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production

John E. S. Park,
Dongmin Shao,
Paul D. Upton,
Patricia deSouza,
Ian M. Adcock,
Rachel J. Davies,
Nicholas W. Morrell,
Mark J. D. Griffiths,
Stephen J. Wort

Published: January 27, 2012
https://doi.org/10.1371/journal.pone.0030075

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28 Feb 2013
23:53 GMT
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Corrections to Figures Posted by PLOS_ONE_Group on 28 Feb 2013 at 23:53 GMT

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Small interfering RNA
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Endothelial cells
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MAPK signaling cascades
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SMAD signaling
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