Site-Directed Mutations and the Polymorphic Variant Ala160Thr in the Human Thromboxane Receptor Uncover a Structural Role for Transmembrane Helix 4

• Raja Chakraborty,

  Affiliation Department of Oral Biology, University of Manitoba, Winnipeg, Manitoba, Canada

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• Sai Prasad Pydi,

  Affiliation Department of Oral Biology, University of Manitoba, Winnipeg, Manitoba, Canada

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• Scott Gleim ,

  Affiliation Section of Cardiology, Department of Internal Medicine, School of Medicine, Yale University, New Haven, Connecticut, United States of America

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• Shyamala Dakshinamurti,

  Affiliations Departments of Pediatrics and Physiology, University of Manitoba, Winnipeg, Manitoba, Canada, Manitoba Institute of Child Health, Winnipeg, Manitoba, Canada

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• John Hwa,

  Affiliation Section of Cardiology, Department of Internal Medicine, School of Medicine, Yale University, New Haven, Connecticut, United States of America

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• Prashen Chelikani

  * E-mail: chelikan@cc.umanitoba.ca

  Affiliations Department of Oral Biology, University of Manitoba, Winnipeg, Manitoba, Canada, Manitoba Institute of Child Health, Winnipeg, Manitoba, Canada

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