Apoptosis Signal-Regulating Kinase 1 Mediates MPTP Toxicity and Regulates Glial Activation

Kang-Woo Lee; Xin Zhao; Joo-Young Im; Hilary Grosso; Won Hee Jang; Teresa W. Chan; Patricia K. Sonsalla; Dwight C. German; Hidenori Ichijo; Eunsung Junn; M. Maral Mouradian

doi:10.1371/journal.pone.0029935

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Peer-reviewed

Research Article

Apoptosis Signal-Regulating Kinase 1 Mediates MPTP Toxicity and Regulates Glial Activation

Kang-Woo Lee,

Affiliation Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
⨯
Xin Zhao,

Affiliation Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
⨯
Joo-Young Im,

Affiliation Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
⨯
Hilary Grosso,

Affiliation Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
⨯
Won Hee Jang,

Affiliation Department of Biochemistry, College of Medicine, Inje University, Busan, Korea
⨯
Teresa W. Chan,

Affiliation Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
⨯
Patricia K. Sonsalla,

Affiliation Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
⨯
Dwight C. German,

Affiliation Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Hidenori Ichijo,

Affiliation Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan
⨯
Eunsung Junn,

Affiliation Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
⨯
M. Maral Mouradian

* E-mail: Mouradian@umdnj.edu

Affiliation Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
⨯

Apoptosis Signal-Regulating Kinase 1 Mediates MPTP Toxicity and Regulates Glial Activation

Kang-Woo Lee,
Xin Zhao,
Joo-Young Im,
Hilary Grosso,
Won Hee Jang,
Teresa W. Chan,
Patricia K. Sonsalla,
Dwight C. German,
Hidenori Ichijo,
Eunsung Junn

Published: January 10, 2012
https://doi.org/10.1371/journal.pone.0029935

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