OTUB1 Overexpression in Mesangial Cells Is a Novel Regulator in the Pathogenesis of Glomerulonephritis through the Decrease of DCN Level

Yan Zhang; Ruimin Hu; Huijuan Wu; Weina Jiang; Yu Sun; Yan Wang; Yanan Song; Tong Jin; Hongxia Zhang; Xin Mao; Zhonghua Zhao; Zhigang Zhang

doi:10.1371/journal.pone.0029654

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Open Access

Peer-reviewed

Research Article

OTUB1 Overexpression in Mesangial Cells Is a Novel Regulator in the Pathogenesis of Glomerulonephritis through the Decrease of DCN Level

Yan Zhang,

Affiliation Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯
Ruimin Hu,

Affiliation Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯
Huijuan Wu,

Affiliation Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯
Weina Jiang,

Affiliation Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯
Yu Sun,

Affiliation Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯
Yan Wang,

Affiliation Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯
Yanan Song,

Affiliation Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯
Tong Jin,

Affiliation Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯
Hongxia Zhang,

Affiliation Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯
Xin Mao,

Affiliation Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯
Zhonghua Zhao,

Affiliation Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯
Zhigang Zhang

* E-mail: zzg@shmu.edu.cn

Affiliation Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯

OTUB1 Overexpression in Mesangial Cells Is a Novel Regulator in the Pathogenesis of Glomerulonephritis through the Decrease of DCN Level

Yan Zhang,
Ruimin Hu,
Huijuan Wu,
Weina Jiang,
Yu Sun,
Yan Wang,
Yanan Song,
Tong Jin,
Hongxia Zhang,
Xin Mao

Published: January 18, 2012
https://doi.org/10.1371/journal.pone.0029654

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Immunoprecipitation
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Transfection
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Glomeruli
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Immunohistochemistry techniques
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Kidneys
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Ubiquitination
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Glomerulonephritis
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Reverse transcriptase-polymerase chain reaction
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