Ablation of Mrds1/Ofcc1 Induces Hyper-γ-Glutamyl Transpeptidasemia without Abnormal Head Development and Schizophrenia-Relevant Behaviors in Mice

Tetsuo Ohnishi; Kazuo Yamada; Akiko Watanabe; Hisako Ohba; Toru Sakaguchi; Yota Honma; Yoshimi Iwayama; Tomoko Toyota; Motoko Maekawa; Kazutada Watanabe; Sevilla D. Detera-Wadleigh; Shigeharu Wakana; Takeo Yoshikawa

doi:10.1371/journal.pone.0029499

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Open Access

Peer-reviewed

Research Article

Ablation of Mrds1/Ofcc1 Induces Hyper-γ-Glutamyl Transpeptidasemia without Abnormal Head Development and Schizophrenia-Relevant Behaviors in Mice

Tetsuo Ohnishi ,

* E-mail: tohnishi@brain.riken.jp

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Japan
⨯
Kazuo Yamada,

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Japan
⨯
Akiko Watanabe,

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Japan
⨯
Hisako Ohba,

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Japan
⨯
Toru Sakaguchi,

Affiliations Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Japan, Department of Bioenginering, Nagaoka University of Technology, Nagaoka, Japan
⨯
Yota Honma,

Affiliations Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Japan, Department of Bioenginering, Nagaoka University of Technology, Nagaoka, Japan
⨯
Yoshimi Iwayama,

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Japan
⨯
Tomoko Toyota,

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Japan
⨯
Motoko Maekawa,

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Japan
⨯
Kazutada Watanabe,

Affiliation Department of Bioenginering, Nagaoka University of Technology, Nagaoka, Japan
⨯
Sevilla D. Detera-Wadleigh,

Affiliation Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, Maryland, United States of America
⨯
Shigeharu Wakana,

Affiliation Technology and Development Team for Mouse Phenotype Analysis, RIKEN BioResource Center, Tsukuba, Japan
⨯
Takeo Yoshikawa

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Japan
⨯

Ablation of Mrds1/Ofcc1 Induces Hyper-γ-Glutamyl Transpeptidasemia without Abnormal Head Development and Schizophrenia-Relevant Behaviors in Mice

Tetsuo Ohnishi,
Kazuo Yamada,
Akiko Watanabe,
Hisako Ohba,
Toru Sakaguchi,
Yota Honma,
Yoshimi Iwayama,
Tomoko Toyota,
Motoko Maekawa,
Kazutada Watanabe

Published: December 29, 2011
https://doi.org/10.1371/journal.pone.0029499

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