Neonatal Androgenization Exacerbates Alcohol-Induced Liver Injury in Adult Rats, an Effect Abrogated by Estrogen

Whitney M. Ellefson; Ashley M. Lakner; Alicia Hamilton; Iain H. McKillop; Herbert L. Bonkovsky; Nury M. Steuerwald; Yvette M. Huet; Laura W. Schrum

doi:10.1371/journal.pone.0029463

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Peer-reviewed

Research Article

Neonatal Androgenization Exacerbates Alcohol-Induced Liver Injury in Adult Rats, an Effect Abrogated by Estrogen

Whitney M. Ellefson,

Affiliation Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina, United States of America
⨯
Ashley M. Lakner,

Affiliation Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina, United States of America
⨯
Alicia Hamilton,

Affiliation Molecular Biology Core Facilities, Carolinas Medical Center, Charlotte, North Carolina, United States of America
⨯
Iain H. McKillop,

Affiliations Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina, United States of America, Department of General Surgery, Carolinas Medical Center, Charlotte, North Carolina, United States of America, Liver-Biliary-Pancreatic Center, Carolinas Medical Center, Charlotte, North Carolina, United States of America
⨯
Herbert L. Bonkovsky,

Affiliations Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina, United States of America, Department of Internal Medicine, Carolinas Medical Center, Charlotte, North Carolina, United States of America, Liver-Biliary-Pancreatic Center, Carolinas Medical Center, Charlotte, North Carolina, United States of America
⨯
Nury M. Steuerwald,

Affiliations Molecular Biology Core Facilities, Carolinas Medical Center, Charlotte, North Carolina, United States of America, Liver-Biliary-Pancreatic Center, Carolinas Medical Center, Charlotte, North Carolina, United States of America
⨯
Yvette M. Huet,

Affiliation Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina, United States of America
⨯
Laura W. Schrum

* E-mail: laura.schrum@carolinashealthcare.org

Affiliations Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina, United States of America, Department of Internal Medicine, Carolinas Medical Center, Charlotte, North Carolina, United States of America, Liver-Biliary-Pancreatic Center, Carolinas Medical Center, Charlotte, North Carolina, United States of America
⨯

Neonatal Androgenization Exacerbates Alcohol-Induced Liver Injury in Adult Rats, an Effect Abrogated by Estrogen

Whitney M. Ellefson,
Ashley M. Lakner,
Alicia Hamilton,
Iain H. McKillop,
Herbert L. Bonkovsky,
Nury M. Steuerwald,
Yvette M. Huet,
Laura W. Schrum

Published: December 20, 2011
https://doi.org/10.1371/journal.pone.0029463

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