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Open Access

Peer-reviewed

Research Article

Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE^−/− Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation

Tin Kyaw ,

* E-mail: Tinsoe.Kyaw@bakeridi.edu.au

Affiliations Vascular Biology and Atherosclerosis Laboratory, Baker IDI Heart and Diabetes Institute, Victoria, Australia, Centre for Inflammatory Diseases, Department of Medicine, Southern Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia
⨯
Christopher Tay,

Affiliations Vascular Biology and Atherosclerosis Laboratory, Baker IDI Heart and Diabetes Institute, Victoria, Australia, Centre for Inflammatory Diseases, Department of Medicine, Southern Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia
⨯
Hamid Hosseini,

Affiliations Vascular Biology and Atherosclerosis Laboratory, Baker IDI Heart and Diabetes Institute, Victoria, Australia, Centre for Inflammatory Diseases, Department of Medicine, Southern Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia
⨯
Peter Kanellakis,

Affiliation Vascular Biology and Atherosclerosis Laboratory, Baker IDI Heart and Diabetes Institute, Victoria, Australia
⨯
Tahlia Gadowski,

Affiliation Vascular Biology and Atherosclerosis Laboratory, Baker IDI Heart and Diabetes Institute, Victoria, Australia
⨯
Fabeinne MacKay,

Affiliation Department of Immunology, Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia
⨯
Peter Tipping,

Affiliation Centre for Inflammatory Diseases, Department of Medicine, Southern Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia
⨯
Alex Bobik ,

Contributed equally to this work with: Alex Bobik, Ban-Hock Toh

Affiliation Vascular Biology and Atherosclerosis Laboratory, Baker IDI Heart and Diabetes Institute, Victoria, Australia
⨯
Ban-Hock Toh

Contributed equally to this work with: Alex Bobik, Ban-Hock Toh

Affiliation Centre for Inflammatory Diseases, Department of Medicine, Southern Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia
⨯

Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE^−/− Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation

Tin Kyaw,
Christopher Tay,
Hamid Hosseini,
Peter Kanellakis,
Tahlia Gadowski,
Fabeinne MacKay,
Peter Tipping,
Alex Bobik,
Ban-Hock Toh

x

Published: January 4, 2012
https://doi.org/10.1371/journal.pone.0029371

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Atherosclerosis
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B cells
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Macrophages
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T cells
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Enzyme-linked immunoassays
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Inflammation
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Cytokines
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Cytotoxic T cells
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