Bifunctional Anti-Huntingtin Proteasome-Directed Intrabodies Mediate Efficient Degradation of Mutant Huntingtin Exon 1 Protein Fragments

Open Access

Peer-reviewed

Research Article

David C. Butler,

Affiliations Wadsworth Center, New York State Department of Health, Albany, New York, United States of America, Department of Biomedical Sciences, University at Albany, Albany, New York, United States of America
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Anne Messer

* E-mail: messer@wadsworth.org

Affiliations Wadsworth Center, New York State Department of Health, Albany, New York, United States of America, Department of Biomedical Sciences, University at Albany, Albany, New York, United States of America
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Transfection
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Proteasomes
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Solubility
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Cell fusion
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Huntington disease
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In vivo imaging
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Toxicity
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Plasmid construction
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