Thiopurine Methyltransferase Predicts the Extent of Cytotoxicty and DNA Damage in Astroglial Cells after Thioguanine Exposure

Open Access

Peer-reviewed

Research Article

Amira Hosni-Ahmed,

Affiliations Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America, Department of Chemistry, College of Science, Fayoum University, Fayoum, Egypt
⨯
Joseph D. Barnes,

Affiliation Department of Clinical Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Jim Wan,

Affiliation Division of Biostatistics and Epidemiology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Terreia S. Jones

* E-mail: tjones@uthsc.edu

Affiliations Department of Clinical Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America, Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America, Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
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Astrocytes
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DNA damage
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Cytotoxicity
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MTT assay
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Neurological tumors
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