Functional Induction of the Cystine-Glutamate Exchanger System Xc- Activity in SH-SY5Y Cells by Unconjugated Bilirubin

Open Access

Peer-reviewed

Research Article

Functional Induction of the Cystine-Glutamate Exchanger System X_c^- Activity in SH-SY5Y Cells by Unconjugated Bilirubin

Pablo J. Giraudi ,

Contributed equally to this work with: Pablo J. Giraudi, Cristina Bellarosa, Claudio Tiribelli

Affiliation Centro Studi Fegato, Fondazione Italiana Fegato, Trieste, Italy
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Cristina Bellarosa ,

Contributed equally to this work with: Pablo J. Giraudi, Cristina Bellarosa, Claudio Tiribelli

* E-mail: cristina.bellarosa@csf.units.it

Affiliation Centro Studi Fegato, Fondazione Italiana Fegato, Trieste, Italy
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Carlos D. Coda-Zabetta,

Affiliation Centro Studi Fegato, Fondazione Italiana Fegato, Trieste, Italy
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Paolo Peruzzo,

Affiliation Centro Studi Fegato, Fondazione Italiana Fegato, Trieste, Italy
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Claudio Tiribelli

Contributed equally to this work with: Pablo J. Giraudi, Cristina Bellarosa, Claudio Tiribelli

Affiliation Dipartimento Universitario Clinico di Scienze Mediche, Chirurgiche e della Salute, Università Degli Studi di Trieste, Trieste, Italy
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Bilirubin
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Glutathione
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Oxidative stress
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Cellular stress responses
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Small interfering RNA
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Cysteine
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Gene expression
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Neuroblastoma cells
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