Low Dose Aerosol Fitness at the Innate Phase of Murine Infection Better Predicts Virulence amongst Clinical Strains of Mycobacterium tuberculosis

Neus Caceres; Isaac Llopis; Elena Marzo; Clara Prats; Cristina Vilaplana; Dario Garcia de Viedma; Sofía Samper; Daniel Lopez; Pere-Joan Cardona

doi:10.1371/journal.pone.0029010

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Research Article

Low Dose Aerosol Fitness at the Innate Phase of Murine Infection Better Predicts Virulence amongst Clinical Strains of Mycobacterium tuberculosis

Neus Caceres,

Affiliations Unitat de Tuberculosi Experimental, Fundació Institut per a la Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Catalonia, Spain, CIBER Enfermedades Respiratorias, Bunyola, Balears, Spain
⨯
Isaac Llopis,

Affiliation Departament de Física i Enginyeria Nuclear, Escola Superior d'Agricultura de Barcelona, Universitat Politècnica de Catalunya, Castelldefels, Catalonia, Spain
⨯
Elena Marzo,

Affiliations Unitat de Tuberculosi Experimental, Fundació Institut per a la Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Catalonia, Spain, CIBER Enfermedades Respiratorias, Bunyola, Balears, Spain
⨯
Clara Prats,

Affiliation Departament de Física i Enginyeria Nuclear, Escola Superior d'Agricultura de Barcelona, Universitat Politècnica de Catalunya, Castelldefels, Catalonia, Spain
⨯
Cristina Vilaplana,

Affiliations Unitat de Tuberculosi Experimental, Fundació Institut per a la Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Catalonia, Spain, CIBER Enfermedades Respiratorias, Bunyola, Balears, Spain
⨯
Dario Garcia de Viedma,

Affiliations CIBER Enfermedades Respiratorias, Bunyola, Balears, Spain, Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital Gregorio Marañón, Madrid, Spain
⨯
Sofía Samper,

Affiliations CIBER Enfermedades Respiratorias, Bunyola, Balears, Spain, Instituto Aragonés de Ciencias de la Salud, Zaragoza, Spain, Hospital Universitario Miguel Servet, Zaragoza, Spain
⨯
Daniel Lopez,

Affiliation Departament de Física i Enginyeria Nuclear, Escola Superior d'Agricultura de Barcelona, Universitat Politècnica de Catalunya, Castelldefels, Catalonia, Spain
⨯
Pere-Joan Cardona

* E-mail: pjcardona@igtp.cat

Affiliations Unitat de Tuberculosi Experimental, Fundació Institut per a la Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Catalonia, Spain, CIBER Enfermedades Respiratorias, Bunyola, Balears, Spain
⨯

Low Dose Aerosol Fitness at the Innate Phase of Murine Infection Better Predicts Virulence amongst Clinical Strains of Mycobacterium tuberculosis

Neus Caceres,
Isaac Llopis,
Elena Marzo,
Clara Prats,
Cristina Vilaplana,
Dario Garcia de Viedma,
Sofía Samper,
Daniel Lopez,
Pere-Joan Cardona

Published: January 3, 2012
https://doi.org/10.1371/journal.pone.0029010

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